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Biomedical subjects

M Sargent

Publications and source records attributed to M Sargent.

At least 19 recordsLinked to original sources
PubMed1990

Panic disorder.

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Alprazolam↗
PubMed1988

Reduced pH increases recovery from radiation damage potentially leading to cell death and to in vitro transformation.

C3H-10T1/2 cells were grown to plateau phase and assessed for recovery from radiation damage under acidic and normal pH conditions. Repair of potentially lethal damage (PLD) was observed after X-ray doses of 5.0, 6.0 and 12.0 Gy and repair increased with dose. The repair at an acidic pH of 6.8 was greater than at the normal pH of 7.4. Repair of potentially transforming damage (PTD) was also observed when cells were held in plateau phase after irradiation. Repair of PTD was greater at the acidic pH than at the normal pH. When PTD recovery was plotted vs PLD recovery the results showed a good linear correlation with approximately twice as much PTDR. The experimental conditions allowing PLDR and PTDR indicate that the repair process may be error-free, since transformation was reduced in all experiments which showed recovery from PLD.

Animals↗
PubMed1985

Ego development in college.

Using the Sentence Completion Test for ego development, we studied several cohorts of students between 1971 and 1979 at a technological institute (Tech) and between 1974 and 1979 at a predominantly liberal arts university (MU). Ego level tended to rise slightly except among women at MU, for whom there was a slight but consistent loss. This particular finding challenges one assumption of a widely accepted version of Piagetian theory: that stage development is irreversible. Women tended to enter MU slightly ahead of men in ego level, but left at the same level. Contrary to expectation, men and women appeared to gain more at Tech than at MU; the difference was significant only for women.

Age Factors↗