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Biomedical subjects

M Salem

Publications and source records attributed to M Salem.

63 records · Page 4Linked to original sources
PubMedDate not supplied

Nephropathogenic infectious bronchitis in Pennsylvania chickens 1997-2000.

Nephropathogenic infectious bronchitis (NIB) was diagnosed in 28 infectious bronchitis virus (IBV)-vaccinated commercial chicken flocks in Pennsylvania from December 1997 to July 2000. Early dinical signs were increased flock mortality and urinary water loss (polyuria and pollakiuria) leading to wet litter. Daily mortality ranged from 0.01% in layers to 2.45% in broilers, with total broiler mortality as high as 23%. Severe renal swelling and accumulation of urates in the tubules were commonly seen. Visceral gout and urolithiasis were less frequently observed. Histopathologic changes included characteristic tubular epithelial degeneration and sloughing with lymphoplasmacytic interstitial nephritis. Minimal respiratory disease signs were noted in broilers. Egg production and shell quality declined in layers. Confirmatory diagnosis of NIB was made by IBV antigen-specific immunohistochemical staining of the renal tubular epithelium and virus isolation. Sequencing of the S1 subunit gene of 21 IBV isolates showed the NIB outbreak to be associated with two unique genotypes, PA/Wolgemuth/98 and PA/171/99. The cases from which the genotypes were isolated were clinically indistinguishable. The NIB viruses were unrelated to previously recognized endemic strains in Pennsylvania and were also dissimilar to each other. Genotype PA/Wolgemuth/98 was isolated almost exclusively during the first 14 mo of the outbreak, whereas PA/171/99 was recovered during the final 18 mo. The reason for the apparent replacement of PA/Wolgemuth/98 by PA/171/99 is not known.

Animals↗
PubMedDate not supplied

Risk factors associated with complications of orbital surgery in children.

PURPOSE: To assess the overall complication rate of orbitotomies performed in children and to determine the nature of complication to identify possible risk factors. METHODS: Thirty children <13 years underwent 33 orbitotomies for space-occupying lesions of the orbit or orbital decompression. A detailed evaluation of the surgical procedures and outcomes was conducted. Follow up averaged 2.5 years (range: 6 months to 5 years). RESULTS: The complication rate was 20% (2 of 10 cases) for anterior orbitotomies, 40% (8 of 20 cases) for primary lateral orbitotomies, and 100% (3 of 3 cases) for secondary orbitotomies. Dense amblyopia was noted in 6 of 9 patients. Major complications were frozen eyeball, diplopia, and ptosis. Less serious complications were enophthalmos, internal ophthalmoplegia, dry eye, and eyelid retraction. Six patients underwent extraocular surgery, levator muscle surgery, or both at a later date. CONCLUSION: Although the scope of complications is the same in children as in adults, the frequency of cystic benign lesions and small orbits in children can cause more frequent serious complications. Additionally, dense amblyopia of a complicated nature makes visual outcome unpredictable. The most significant risk factors identified were the need for a secondary procedure for recurring pathology and the presence of an intraconal lesion.

Adolescent↗
PubMedDate not supplied

Risk factors associated with early respiratory disease complex in broiler chickens.

Early respiratory disease complex (ERDC) is a term coined to describe an acute disease characterized by depression, respiratory distress, and increased mortality in 2-to-3-wk-old broiler chickens. Postmortem lesions include airsacculitis, fibrinous pericarditis, and perihepatitis. Colisepticemia is the primary cause of death. In order to investigate the association between ERDC and farm management factors, a retrospective case-control study was conducted by collecting data covering a 6-mo period (January-June 1997) from four broiler integrators on the Delmarva peninsula. Univariate and multivariate statistical analyses revealed that flock size was positively associated (P = 0.02) and layout time was negatively associated (P = 0.05) with ERDC.

Acute Disease↗
PubMedDate not supplied

Pullorum disease in Delaware roasters.

An index case of pullorum disease in 4-week-old roasters from a completely integrated poultry operation is reported from Delaware. Severe articular and periarticular swelling of hock and/or wing joints was observed on postmortem examination. Also seen were moderate to severe hydropericardium and large white-gray nodules in the heart and gizzard that grossly could have been taken for tumors. The livers showed multiple small white foci, petechial hemorrhages, and swelling. Initially, Salmonella pullorum was isolated from the articular fluid by direct culture on MacConkey agar, but it was not isolated from liver, spleen, or heart samples after enrichment in selenite broth.

Animals↗
PubMedDate not supplied

Isolation and identification of Ornithobacterium rhinotracheale from commercial broiler flocks on the Delmarva peninsula.

The growth and biological characteristics of isolates of Ornithobacterium rhinotracheale (ORT) from commercial broiler chickens in the mid-Atlantic region of the U.S.A. appear to be identical to those previously reported in the literature. The clinical disease and lesions are also similar to those reported from other poultry growing regions including South Africa and Europe. The diagnostic cases included in this report were often associated with known respiratory pathogens, namely, lentogenic Newcastle disease virus, and infectious bronchitis virus, and Escherichia coli bacteria. The role of ORT in the disease cases presented in this report is unclear.

Animals↗