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Biomedical subjects

M Sage

Publications and source records attributed to M Sage.

At least 55 records · Page 3Linked to original sources
PubMed1983

[Malignant adrenal cortex tumors responsible for primary hyperaldosteronism and biological hypercorticism. Remarks apropos of 2 surgically-treated cases].

Two cases of malignant adrenal cortex tumors revealed by primary hyperaldosteronism with hypertension, and associated with a biological hypercortisonism, are reported. Diagnosis of this very rare affection depends on the finding of marked biological hyperaldosteronism associated with a large adrenal tumor. The outcome appears to be rapidly fatal for tumors exceeding 5 cm in diameter and associated with lymph node invasion. This raises the problem of the utility of surgery in these cases, operative intervention apparently accelerating progression of the lesion. In practice, however, a laparotomy is always justifiable, the most rational biopsy being excision of the tumor.

Adrenal Cortex Neoplasms↗
PubMed1981

Rapid serial cranial computed tomography for tumor diagnosis.

Rapid serial computed tomography (RSCT) provides more information about the cerebral cortical capillary bed and leptomeningeal vessels than conventional enhanced computed tomography (CT). This increased neuroanatomical definition has potential value for separating intra- from extracerebral tumors in selected cases. RSCT offers better visualization of the angioarchitecture of highly vascular tumors than conventional enhanced CT. However, CT scans delayed several minutes after contrast administration are more useful for evaluating the extent of hypovascular tumors. Time-density curves were of limited value for tumor evaluation. However, the peak increase of Hounsfield units did correlate well with the degree of tumor vascularity assessed angiographically.

Adult↗
PubMed1981

Case report. Malignant change in an intracranial epidermoid cyst.

A malignant epidermoid tumor invading the fourth ventricle had histologic features that indicated malignant transformation in a benign epidermoid cyst. The computed tomographic (CT) findings correlated precisely with the histologic features, revealing both pathologic enhancement and a low attenuation zone. The spectrum of described CT findings in intracranial epidermoids is reviewed and contrasted with the appearance encountered in the present case.

Brain Neoplasms↗
PubMed1981

[True traumatic aneurysm of the proximal part of the brachial artery without osteo-articular lesions : a rare condition. A case report (author's transl)].

True isolated traumatic aneurysms are very rarely observed, and have to be differentiated from false aneurysms. They correspond to unrecognized arterial contusions following closed shoulder injuries. The presence of a large hematoma in the axillohumeral region, associated with an early ecchymosis, should suggest the possibility of an arterial lesion, and arteriography should be conducted. Difficulty in diagnosing the lesion clinically arises from the particular location of such lesions and the richness of the brachial and axillary artery collaterals. This latter fact explains why an ischemic syndrome is rarely observed. Treatment of true traumatic aneurysms is always surgical.

Adult↗
PubMed1977

[Vascularization of the transverse colon].

Results of 21 injections of the transverse colon with coloured latex. The superior and inferior mesenteric arteries are separately injected. Dissections allowed the study of the topography and width of the colic transverse vessels. Collateral circulation is also described. A middle colic artery is present in 85% of the cases. The length of transverse colon vascularized by each arterial system is related with accuracy to the number of arcades issued from each system. The superior mesenteric artery prevails in the blood supply of the transverse colon (70% of its length).

Colon↗
PubMed1975

The autoregulatory capability of Galen's rete cerebri and its connections.

The rete, a vascular system between the extra- and intracerebral arteries of certain animals, may have a variety of functions in different species. The calibres of the vessels of the rete and its arteries of supply have been measured under different conditions of blood pressure and PaCO2. It has been shown that the rete and its afferent arteries behave in an autoregulatory fashion down to a blood pressure of 60 mmHg. They also dilate with a rise in PaCO2. It has also been found that some parts of the system dilate even when the blood pressure drops lower than 60 mmHg. It is suggested that this autoregulatory capacity of extradural vessels limits the requirement for CSF spaces to change with blood pressure changes. A general rule has been sought which would link the known facts about cerebral autoregulation and the possession of extra- to intracranial anastomoses with the bodily shape and posture of the particular animal.

Animals↗
PubMed1975

The vasodilator action of angiography with Urografin 60% on the basal vessels of the brain of the baboon.

Angiography under experimental conditions shows that Urografin has a vasodilator action of the order of 8% upon the basal cerebral arteries of the baboon. This action is not seen within the first 4 sec of the angiogram and the dilator effect of a single injection has passed off completely 15 min later. Three successive injections within 7 min show little evidence of cumulative vasodilatation. The vasodilator action of three successive angiograms has disappeared 22 to 29 min later. Because of wide variations in the degree of vasodilatation shown by individual baboons it may be necessary to use each baboon as its own control in subsequent work.

Angiography↗