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Biomedical subjects

M Safar

Publications and source records attributed to M Safar.

At least 379 records · Page 21Linked to original sources
PubMedDate not supplied

[Study of 104 patients with renal polycystic disease (author's transl)].

Hereditary factors were observed in 43% of patients. Hypertension was observed in 45% of cases and was not correlated with the degree of renal insufficiency. Serum creatinine was significantly correlated with calcemia and uricemia. Identical correlations were observed in a population of patients whose renal insufficiency was not related to renal polycystic disease. The study provides evidence that, in polycystic kidneys: 1) Hypertension is not related to the degree of renal failure. 2) Hypocalcemia and hyperuricemia are not specific factors of the disease.

Adolescent↗
PubMedDate not supplied

[Diuretics and uric acid (author's transl)].

Long-term diuretic therapy often increases serum uric acid. The renal metabolism of uric acid is recalled and the factors which lead to diuretic-induced hyperuricemia are discussed. Fluid and sodium loss appears to be the main cause of increased serum uric acid. The authors' experience with management of severe hypertension is consistent with this theory. The effect of tienilic acid which lowers serum uric acid levels is discussed.

Adult↗