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Biomedical subjects

M Safak

Publications and source records attributed to M Safak.

27 records · Page 2Linked to original sources

Histopathological alterations of deep dorsal penile vein in venogenic impotence.

The mechanism and hemodynamics of penile veins in erection have long been a matter of controversy and hypotheses. With the intention to develop a new concept of venous ultrastructure in penile venous insufficiency, we studied the histopathology of 13 dorsal penile veins obtained from important patients during venous ligation because of proven venous leakage. Besides, 1 normal deep dorsal vein taken from a volunteer who underwent another type of penile operation was also examined. All sections were stained with hematoxylineosin, Gomori trichrome, periodic acid-Schiff, Gomori reticulum and Verhoeff elastic stains. All 13 veins showed some significant histological changes namely nodular hypertrophy in 7, nodular atrophy in 2, diffuse atrophy in 2, diffuse hypertrophy in 1 and minimal changes in 1. In general, the dominating histological appearance was hypertrophy of the muscular pattern and enhancement of collagenization. None of these alterations was prevalent in the normal control. The cause and the result relationship between venous leakage and the mentioned histological changes still remains a matter of debate.

Adult↗

Intrascrotal extratesticular malignant schwannoma.

We report a rare case of intrascrotal extratesticular malignant schwannoma with rhabdomyoblastic features in a 48-year-old man. Malignant schwannomas, which arise from the peripheral nerves, usually occur in the extremities, the trunk or paravertebral areas. The patient had no manifestation of von Recklinghausen's disease. To our knowledge, there has been no intrascrotal extratesticular malignant schwannoma reported.

Genital Neoplasms, Male↗

Treatment of impotence due to venous leakage by resection of the deep dorsal vein of the penis.

Ligation and resection of the deep dorsal vein of the penis is a surgical approach to restore potency in venogenic impotence. Between December 1989 and December 1990, we treated 25 men with venogenic impotence by this technique. Additionally, the Nesbit operation was performed in 3 cases due to penile curvature and in 1 case a penile plaque was excised. The patients were asked to come for control 1, 3, 6 and 12 months after surgery. In 14 patients the rigidity and duration of erections were improved 3 months after surgery but, in 21 of the 25 men, erectile dysfunction recurred 6-15 months (average 9.4 months) following surgery and penile prostheses were implanted in 7 cases. The complications were orchiepididymitis in 1 case, penile edema and hyperemia which lasted for 1 week in 1 patient and numbness near the incision site in 10 cases. We conclude that, in patients who had erectile impotence due to venous leakage, resection of the deep dorsal vein of the penis could provide a transient satisfactory result, but should not be considered as a long-term treatment modality.

Adult↗

Vas deferens calculus.

We describe a patient with a radiopaque calculus in the vas deferens that was inappropriately diagnosed as a ureteral calculus.

Calculi↗

Intrarenal lipoma: report of a case.

We recently had the opportunity to study a case of renal lipoma. Pure intrarenal lipomas are very infrequent among all of the renal tumors and computed tomography is the only means of showing the fatty nature of such masses with its contrast discrimination property.

Female↗

Emphysematous pyelonephritis with pneumocystitis.

Emphysematous pyelonephritis is an acute infectious process mostly associated with diabetes and obstruction. It is a life-threatening illness and treatment generally involves antibiotic therapy, surgical drainage and nephrectomy. The prognosis is poor regardless of therapy. Herein, we present a case with pneumocystitis. To our knowledge, there have been 54 cases previously reported. There is no doubt that emphysematous pyelonephritis with pneumocystitis as in our case is less frequent.

Air↗

Milk of calcium hydronephrosis.

There are very few reported cases of 'milk of renal calcium' since Holm's first presentation of this rare condition in 1948 [Rosenberg, J. Urol., 101: 714, 1967]. We recently had the opportunity to study 2 more cases, which are described herein.

Adult↗