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Biomedical subjects

M Sacher

Publications and source records attributed to M Sacher.

At least 127 records · Page 7Linked to original sources
PubMed1977

[Lipoprotein-x determination in children beyond an age of 6 months (author's transl)].

In premature and newborn infants an abnormal lipoprotein (LP-X) was almost regularly detectable by examination up to the 24th week after deliver. The aim of the submitted study was to evaluate LP-X results in children older than 6 months. 250 sera of 158 infants of all age groups were tested for presence of LP-X. The frequency of LP-X positive results was 85.7% in the group of infants younger than 24 weeks (91 samples of 45 infants were tested) whereas in the group of infants of an age between 24 weeks and 14 years (159 samples of 113 children were tested) 16.35% positive results were obtained. LP-X positive results showed the same clinical significance in the second group of children as it was demonstrated in adults elsewhere.

Age Factors↗
PubMedDate not supplied

Successful closure of the patent ductus arteriosus by indomethacin in an extremely low birth weight infant of very advanced postnatal age.

Many studies demonstrate the efficacy of closure of a patent ductus arteriosus with indomethacin, but also show that success diminishes markedly with increasing postnatal age. For this reason surgical ligation is usually preferred after the first month of life. We describe the case of a male premature infant (25 weeks gestation, birth weight 680 g), in whom a PDA was successfully closed with indomethacin (0.1 mg/kg once daily intravenously for 6 days) at the age of 11 weeks. Thus it may be concluded that closure by drug may be attempted before surgical ligation even in cases of advanced postnatal age.

Cyclooxygenase Inhibitors↗
PubMedDate not supplied

[Effectiveness and complications of percutaneous central venous catheters in neonatal intensive care].

Low birth weight babies and sick full-term babies, who require total parenteral nutrition and repeated intravenous applications of drugs, which irritate peripheral veins, very often need a reliable central venous catheter. The aim of our paper was to study prospectively the efficiency and the complications of peripheral percutaneous Silastic-catheters. Over a period of 9 month we inserted 114 central venous catheters via peripheral veins in 111 premature babies and sick full-term infants at our neonatal intensive care unit. The mean duration of use was 13.7 days, the catheter-induced septicaemia-rate was 3.5%. We never saw serious complications of a central venous catheter, the most common complication was an intravasal central obstruction, but we found no relation between the occurrence-risk of complications, the duration of use and the infusion flow rate.

Birth Weight↗
PubMedDate not supplied

Two benign CT presentations of thyroid-related papillary adenocarcinoma.

Two cases of thyroid-related papillary adenocarcinoma are presented. Both patients had clinically benign neck masses that were clearly separated from the thyroid gland. In both cases the thyroid gland was normal to clinical evaluation, CT, and 99mTc scanning. One patient had an occult thyroid carcinoma with a solitary metastatic node in the lateral neck, and the other patient had a rare carcinoma in a suprahyoid thyroglossal duct cyst that had been previously misdiagnosed as a cystic hygroma.

Adenocarcinoma, Papillary↗
PubMedDate not supplied

Internal jugular vein phlebectasia and duplication: CT features.

Phlebectasia of the internal jugular vein (IJV) is a rare entity with only 25 cases having been reported. Clinically this condition presents with enlargement with a Valsalva maneuver and decrease at rest. Venography, anteriography, and ultrasound have previously been used to diagnose this unusual cause of neck mass. We present a case in which CT confirmed the clinical diagnosis and in which there was an incomplete ipsilateral duplication of the IJV. This is only the second case reported of IJV phlebectasia and duplication.

Aged↗
PubMedDate not supplied

CT myelography of spontaneous spinal epidural hematoma.

A case of so-called spontaneous epidural hematoma is presented. A new constellation of myelographic and CT myelographic signs are described that may assist in localizing a mass within the spinal epidural space.

Adolescent↗
PubMedDate not supplied

CT changes in the septum pellucidum associated with intraventricular craniopharyngiomas.

Although intraventricular craniopharyngiomas are usually located within the suprasellar cistern, they may arise from the floor of the third ventricle or lamina terminalis. Four cases of intraventricular craniopharyngioma are presented in which the CT findings included thickening or separation of the leaves of the septum pellucidum. The importance of this CT finding and its possible etiologies are discussed.

Adult↗
PubMedDate not supplied

Computed tomography of solitary spinal osteochondromas.

Solitary osteochondromas rarely occur in the axial skeleton. These benign tumors may cause a variety of symptoms while remaining difficult to recognize by plain radiographic and myelographic studies. We present three cases of solitary osteochondromas of the spine and demonstrate the CT findings of these unusual tumors.

Adolescent↗
PubMedDate not supplied

Intraosseous petrous apex neuroma: CT findings.

An avascular, contrast enhancing intraosseous petrous apex mass was discovered on CT in a patient with prior colonic carcinoma and acute myelocytic leukemia. A normal bone scan made metastasis unlikely and surgery revealed a neuroma. The differential diagnosis is discussed.

Humans↗
PubMedDate not supplied

Kissing intrasellar carotid arteries in acromegaly: CT demonstration.

Acromegaly is a disease with protean manifestations that are well described in the literature. One finding infrequently encountered is aneurysmal dilatation of the internal carotid arteries and their branches. A case is presented, with CT documentation, in which the enlarged cavernous portions of the internal carotid arteries prolapsed into the sella turcica and enlarged it. Frontal bossing, frontal sinus enlargement, a dense cortical calvarium, prominent inion, and proptosis secondary to extraocular muscular enlargement were findings also present in this patient. The sella CT appearance has brought the term "kissing intrasellar arteries" to mind to suggest the diagnosis.

Acromegaly↗
PubMedDate not supplied

CT appearance distinguishing benign nasal polyps from malignancies.

In many cases the common nasal polyp is confused clinically, radiographically, and, on occasion, pathologically with a tumor of the nasal vault and paranasal sinuses. Similarly, this distinction often cannot be made by CT. However, we have identified in 12 patients a CT appearance of looping, minimally or nonenhancing soft tissue densities within a mucoid density background matrix, that is associated with cases of polyposis (nine patients) and fungal disease (three patients). We believe that when this CT appearance is present, malignant disease can be essentially eliminated from the differential diagnosis.

Aspergillosis↗
PubMedDate not supplied

Paget disease of the calvaria and facial bones with an osteosarcoma of the maxilla: CT and MR findings.

The CT and magnetic resonance (MR) findings of Paget disease of the calvaria and facial bones are described and compared with one another. The sites of dense, woven bone, myeloid marrow, and background Paget matrix can be clearly identified. A rare case of Paget sarcoma (osteogenic sarcoma) of the facial bones is also presented. The distinction between this sarcoma and the Paget bone was clearer on CT than on MR. This presumably is because the bone is directly seen on CT and only indirectly imaged on MR.

Angiography↗
PubMedDate not supplied

Benign and malignant parotid pleomorphic adenomas: CT and MR studies.

Parotid pleomorphic adenomas are usually benign, solitary, ovoid masses. Occasionally, these tumors may be highly lobulated and clinically mimic multiple lesions. Actual multiple benign mixed tumors are rare as are malignancies that occur in these pleomorphic adenomas. Of these malignancies, the most common type is the carcinoma ex pleomorphic adenoma. Two patients are presented, one of whom had a markedly lobulated benign mixed tumor and the other patient had an ex pleomorphic malignancy associated with multiple benign mixed tumors. Both cases are documented with CT and magnetic resonance studies. The relative merits of these modalities are discussed as they apply to these parotid masses.

Adenoma, Pleomorphic↗
PubMedDate not supplied

Ossifying fibroma of sphenoid bone with coexistent mucocele: CT and MRI.

A case of a 26-year-old woman with decreasing vision in her right eye, diplopia, headache, and galactorrhea is presented. Both CT and MR studies showed a large sphenoid fibroosseous lesion that had a ground glass appearance on CT and low-to-intermediate proton density and low T2-weighted and low T1-weighted signal intensities on MR. After contrast medium administration, this process diffusely enhanced on CT and MR. There was also an expansile mass in the sphenoid sinus that had intermediate proton density, high T2-weighted and low T1-weighted signal intensities compared with brain. This mass did not enhance but had an intensely enhancing, uniformly thin rim. The pathologic diagnosis was ossifying fibroma with a sphenoid sinus mucocele. There are only isolated reports in the literature of benign fibrosseous lesions causing mucoceles. This association is reviewed as are the findings in this case.

Adult↗