Biomedical subjects
Publications and source records attributed to M Săninoiu.
It is presented a month old child, with unilateral microphthalmos and bilateral malformations of the auricle, manifestations considered as a form of Goldenhar syndrome. This case bengi in that family, the malformation is considered as a phenocopy resulted from the action of a teratogen factor, beginning from the 21 day of the embryonic life.
The association of the open-angle glaucoma and the retina venous occlusion constitutes an aggravating factor, the two affections influencing to each other. The study of a number of 168 venous obstructions of the retina, 56% of which being obstruction of the central vein and 44% of ramus, have evaluated appearing as edematous capillaropathy for 36% cases, ischemic capillaropathy for 44% and mixed forms for 20% ones. The retina venous occlusions have evaluated for 70% for masculine gender and 30% for feminine. From all the predisposed affections the hypertension and arteriosclerosis were for 58% all over the cases; dyslipidemias for 15%; hypercholesterolemia for 11%, diabetes for 8%. In the occlusion of the venous ramus the opened angle glaucoma, that has preceded thrombosis, was at the same frequency as for the general population, while in the obstruction of the central vein, the opened angle glaucoma has preceded thrombosis for 18% of all the cases, so it may be considered as a favourable factor by slowing down the sangvin flux. The opened-angle glaucoma hasn't influenced the appearing of the retina thrombosis. The second neurovascular glaucoma, an irreducible complication of the ischemic capillaropathy was for 22% of the studied cases. During the presence of a retina venous thrombosis is necessary a systematic examinations of the ocular tension, for finding an opened-angle glaucoma pre-existed to thrombosis.
The author presents a case of the palsy common oculomotor, as a result of an aneurysm of the posterior communicated artery. It is highlighted the importance of the carotinoid angiography in the diagnosis of the affection.
A study based on the casuistics of the Clinic of Ophthalmology of Craiova for a 10 year-period was performed, pointing out the presence of 61 cases of uveitis among children aged 0-16 years. This study was deemed useful, since infantile uveitis, less frequent (10 per cent of the total number of cases of uveitis), are often more severe owing to their chronic course and to the prevalence of posterior forms.
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The 3-years-old patient presents bilateral exophthalmia and papillar stasis at both eyes. The cranial examination shows the frontal boss at the level of the anterior fontanelle and the hypoplasia of the inferior facial floor. The cranial radiography shows digital impressions on the entire projection surface of the cap. The child also presents mental retardation. The affection integrates in the category of craniofacial dysostosis described by Crouzon, maladies which are transmitted autosomal with great penetrance.