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Biomedical subjects

M S Weiss

Publications and source records attributed to M S Weiss.

50 records · Page 3Linked to original sources
PubMed1979

Acoustical and perceptual characteristics of speech produced with an electronic artificial larynx.

Five normal-speaking adult males were taught to produce speech using an electrolarynx. Speech phoneme intelligibility was measured in a closed-set word discrimination test and through phonetic transcriptions of the spoken materials. Mean percentages of correct identification for the five talkers were 90% and 57% for the word-identification test and phonetic transcription, respectively. An analysis of perceptual confusions revealed that errors were most frequently associated with the voicing feature and that few manner or place of articulation errors occurred. Over the range of variables observed, the intensity of both the speech and the noise radiating directly from the electrolarynx, the spectrum of the radiated noise and speaking rate were not found to be determinants of intelligibility.

Acoustics↗
PubMed1979

Masking of filtered noise bursts by synthetic vowels.

The present investigation assessed the simultaneous and temporal masking produced by computer-generated synthetic vowels. The durations (100 and 200 ms) of each of four vowel-like maskers were employed. The masker was presented at 70 dB SPL. The probe signals were three filtered noise bursts whose spectral distributions corresponded to regions of high spectral energy in three English stop consonants. Quiet and masked thresholds were determined using the method of adjustment. Data are reported for two experienced listeners who participated in all the listening conditions. The results were generally in accord with the results of masking experiments using nonspeech signals in that both the frequency specificity of masking and temporal masking effects were demonstrated.

Computers↗
PubMed1979

Post-void residual alerting device.

A simple, inexpensive device is described which alerts nursing staff upon spontaneous voiding by a patient with spinal cord injury. This facilitates measurement of the post-void residual urine volume which is useful in the management of neurogenic bladder.

Humans↗
PubMed1978

Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome.

To assess toxicity of D-penicillamine a retrospective chart review was performed on 63 patients with rheumatoid arthritis receiving penicillamine. These patients had a total of 83 courses of therapy. The mean age of patients was 52 years and the mean duration of disease was 10.07 years. Laboratory data showed an increase in hematocrit values from 36 per cent to 40 per cent and a decrease in the erythrocyte sedimentation rate from an average of 50 to 29 mm/hour. The platelet count also decreased with treatment from 394,000 to 267,000/mm3. The over-all complication rate was 53 per cent. Life-threatening complications occurred in two patients including one case of aplastic anemia and one case of nephrotic syndrome. One additional patient was referred with aplastic anemia. Minor complications include rash in 18 per cent, loss of taste in 6 per cent, dyspepsia in 11 per cent, oral ulceration in 7 per cent and proteinuria of less than 3 g/day in 8 per cent. In summary, 53 per cent of the courses of penicillamine were associated with toxicity including one episode of aplastic anemia and one case of nephrotic syndrome. Therapy was stopped due to complications in 39 per cent of the patients in this series.

Adult↗