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Biomedical subjects

M S Stone

Publications and source records attributed to M S Stone.

At least 37 records · Page 2Linked to original sources
PubMed1994

Rudimentary meningocele presenting with a scalp hair tuft. Report of two cases.

BACKGROUND: Rudimentary meningoceles represent a developmental anomaly in which meningothelial elements are found in the skin. The majority of rudimentary meningoceles occur on the scalp over the occiput or along cranial suture lines. They are usually recognized at birth and present as a pink papule or nodule or an area of alopecia. OBSERVATIONS: We present two patients who presented with a scalp hair tuft at birth over a rudimentary meningocele. This finding has not been previously reported. CONCLUSIONS: Rudimentary meningoceles are uncommon developmental anomalies that are of clinical importance due to the occasional presence of connection to the central nervous system. Due to this potential for central nervous system connection, any midline lesion in an infant, including midline hair tufts, deserves careful preoperative evaluation including imaging studies.

Adult↗
PubMed1993

Cutaneous vasculitis in the newborn of a mother with cutaneous polyarteritis nodosa.

Vasculitis in an infant of a woman who had a long history of cutaneous polyarteritis nodosa is reported. During the neonatal period the child developed cutaneous vasculitis manifested by livedo reticularis, cutaneous nodules, and acral necrosis. The infant's vasculitis remitted by age 7 months. This is the third such report and strongly suggests the presence of a circulating factor that is capable of crossing the placenta and inducing cutaneous polyarteritis nodosa.

Adult↗
PubMed1993

Incontinentia pigmenti: transmission from father to daughter.

Incontinentia pigmenti (IP) is a well-described genodermatosis that occurs almost exclusively in females. IP is characterized by a distinctive skin eruption and a variable presence of multisystem abnormalities. Pedigree analysis is most consistent with an X-linked dominant trait that is lethal in males. However, 27 reports of IP in males have been published, excluding four patients who had Klinefelter's syndrome. It has usually been assumed that these rare affected males survive because of genetic mosaicism. Mosaic inheritance of IP is also strongly supported by the characteristic distribution of skin findings along Blaschko's lines. Only one case of father-to-daughter transmission has been previously reported. We report a second case of father-to-daughter transmission of IP. Chromosomal analysis of blood and fibroblasts from the father failed to provide evidence of genetic mosaicism.

Adult↗
PubMed1992

Paraneoplastic pemphigus, cicatricial conjunctivitis, and acanthosis nigricans with pachydermatoglyphy in a patient with bronchogenic squamous cell carcinoma.

A 77-year-old man with chronic conjunctivitis, acanthosis nigricans with pachydermatoglyphy, and pemphigus-like mucocutaneous lesions was found to have a well-differentiated bronchogenic squamous cell carcinoma. Histopathologic and immunofluorescence studies confirmed the diagnosis of paraneoplastic pemphigus. Skin lesions resolved with oral prednisone and azathioprine therapy, but the conjunctivitis and mucous membrane erosions persisted. The conjunctiva later became scarred with foreshortening of the fornices and development of symblepharon. External beam irradiation arrested the growth of the tumor but did not have any effect on the diseased conjunctiva and other mucous membranes. This case demonstrates that cicatrizing conjunctivitis with bullous mucocutaneous lesions may be a clinical sign associated with an occult neoplasm.

Acanthosis Nigricans↗
PubMed1992

Ultraviolet light burn: a cutaneous complication of visible light phototherapy of neonatal jaundice.

Visible light phototherapy is an easily administered and effective treatment for neonatal indirect hyperbilirubinemia. Reported cutaneous side effects include transient rashes and the uncommon bronze baby syndrome. A more hazardous side effect is ultraviolet burn. Two premature infants developed phototherapy-induced erythema, one associated with a second-degree burn, after exposure to fluorescent daylight bulbs inadvertently used without Plexiglass shields, thus allowing prolonged ultraviolet A (UVA) exposure. Premature infants, especially during the first two weeks of life, may be significantly susceptible to UVA-induced erythema. Plexiglass shields should always be in place during visible light phototherapy, and nursery staff should be made aware of their purpose.

Burns↗
PubMed1992

Lung infections and infestations. Therapeutic considerations.

This article discusses two common causes of lung disease in the dog and cat: tracheobronchitis and bacterial pneumonia. Information about parasitic infestation of the trachea, bronchi, and lung parenchyma is summarized. Data are also presented regarding the sensitivities of bacterial infections of the respiratory tract to antibiotics.

Animals↗
PubMed1989

A cutaneous sign of IgA-associated small dermal vessel leukocytoclastic vasculitis in adults (Henoch-Schönlein purpura).

A series of patients shared the distinctive cutaneous findings of palpable purpuric plaques with multifocal areas of hemorrhage or superficial necrosis within individual lesions and a retiform pattern of hemorrhage, superficial necrosis, or lesional margins. This pattern was looked for in every patient presenting with palpable purpura, but it was seen exclusively in the seven patients described herein. Each patient was found to have an IgA-associated small dermal vessel vasculitis that was proved to be leukocytoclastic in six of the seven patients. These distinctive cutaneous findings may be evidence of the presence of IgA deposition in patients with small-vessel leukocytoclastic vasculitis and may infer a different pathogenesis for lesion formation in some patients with IgA-associated vasculitis.

Adrenal Cortex Hormones↗
PubMed1988

Papular elastorrhexis: a variant of connective tissue nevus. Case reports and review of the literature.

Two unrelated young women with papular elastorrhexis have recently been seen at the University of Iowa Hospitals and Clinics. This entity, recently described in a single patient, is a distinct variant of a connective tissue nevus. Although the histologic features of papular elastorrhexis may mimic those of other connective tissue nevi, clinical characteristics allow differentiation. The clinical and histologic characteristics of papular elastorrhexis, as well as its differential diagnosis, are discussed.

Adult↗
PubMed1987

Bowen's disease of the feet. Presence of human papillomavirus 16 DNA in tumor tissue.

A 36-year-old black man with bilateral squamous cell carcinoma in situ of the feet is described. The DNA hybridization analysis performed on the tumor tissue demonstrated the presence of human papillomavirus 16 DNA. Human papillomavirus 16 has been detected repeatedly in genital carcinomas, and evidence is mounting that it may play an important role in the development of malignancy.

Adult↗
PubMed1987

Acne rosacea in blacks.

Acne rosacea has been considered to be a rare disease among black patients. Three cases of rosacea in blacks are described and illustrated. Acne rosacea may be more common in black patients than heretofore believed.

Black People↗