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Biomedical subjects

M S Rawat

Publications and source records attributed to M S Rawat.

18 recordsLinked to original sources
PubMed2000

Role of vitamin E in rheumatic chorea.

Rheumatic chorea is the sole neurologic manifestation of rheumatic fever. It is a debilitating illness lasting for weeks to months. Drugs like diazepam, haloperidol, chlorpromazine take four to six weeks for functional improvement and can cause serious side effects. The authors investigated the role of Vitamin E in reducing rheumatic chorea. A case series of patients of rheumatic chorea were administered Vitamin E in the dose 50 IU daily for fifteen days. The various clinical signs of rheumatic chorea were scored with MAIMS score (Modified Abnormal Involuntary Movement Scale score) which is used for tardive dyskinesia. No other drug for abnormal movements was used. In all the 4 patients who received vitamin E, there was remarkable change by 7th day and almost complete functional improvement by 14th day. Vitamin E is safer than the conventional drugs used for chorea in children. It was found effective in this case series. Its role needs further evaluation by a double-blind randomized controlled trial.

Child↗
PubMed2000

A new secoiridoid glycoside from Lonicera angustifolia.

A new secoiridoid glycoside, 6'-O-beta-apiofuranosylsweroside (1), together with the known compounds sweroside, loganin, beta-sitosterol, oleanolic acid, ursolic acid and methyl-4-hydroxy benzoate have been identified from the leaves of Lonicera angustifolia. The structure of the new compound has been elucidated on the basis of spectroscopic and chemical evidence.

Glucosides↗
PubMed1998

An A-type proanthocyanidin from Prunus armeniaca.

Roots of Prunus armeniaca yielded a new A-type proanthocyanidin whose structure was assigned as ent-epiafzelechin-3-O-p-hydroxybenzoate-(4alpha-->8, 2alpha-->O-->7)-epiafzelechin (1). The structure of 1 was determined through extensive 1D and 2D NMR studies.

Anthocyanins↗
PubMed1990

ELISA for diagnosis of tuberculosis.

Antigen A 60 of Mycobacterium bovis is a cell wall antigen with almost complete cross reactivity with antigen A 60 of Mycobacterium tuberculosis. This antigen was used for the ELISA technique for 100 cases suspected of childhood tuberculosis to evaluate the usefulness of the method in the diagnosis. The positivity rate in pulmonary tuberculosis was 65.1%, in central nervous system tuberculosis 50.0% and in the miscellaneous group 76.4%. The overall positivity was 61.0%, proving the utility of the method for diagnosis.

Adolescent↗
PubMed1988

Chloramphenicol.

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Bacterial Infections↗
PubMed1967

Trichobezoar.

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Bezoars↗
PubMedDate not supplied

Pulmonary function tests in school children.

Pulmonary Function tests were measured in 261 healthy boys and 254 healthy girls in the age group of 6 to 15 years with standard Benidects Roth type recording spirometer and Wrights Peak Flow Meter. The values of Pulmonary Functions were found to be increased with increase in age. For vital capacity this relation was curvilinear. All values were higher in boys than girls. There was significant positive correlation between pulmonary Function Tests Vital Capacity, (VC), Maximum Voluntary Ventilation (MV), peak Expiratory Flow Rate (PEFR) and anthropometric parameters like height, weight and body surface area. Equations were formed for prediction of V.C., M.V.V. and PEFR values in relation to the height. The values of Pulmonary Functions were lower when compared with Western Standards, but were comparable with different Indian Studies.

Adolescent↗