Cerebral arterial spasm. 2. Experimental evaluation of mechanical and humoral factors in pathogenesis.
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Biomedical subjects
Publications and source records attributed to M S Mahaley.
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The incidence of local nerve injury among 192 consecutive carotid endarterectomies in 162 patients between 1977-1983 was determined from review of the medical records. Two facial nerve, 5 hypoglossal nerve, and 2 vagus nerve injuries were discovered for a total incidence of 4.7%. Only the 2 facial nerve injuries failed to improve over 2 years. Followup ranged from 1 to 60 months in this group of patients. Careful attention to details of tissue dissection at surgery should lower the incidence of nerve injury during carotid endarterectomy.
A technique for analysis of dynamic radionuclide studies of the cerebral circulation is described. This technique permits objective classification of observed radionuclide distribution patterns. Variation in the time-to-peak activity, and in the maximum attained activity as determined by region-of-interest analysis of cerebral hemispheric activity, was defined for a normal population. Application of these normal values permits classification of observed hemispheric radionuclide distribution patterns in anaplastic gliomas and in occlusive cerebrovascular disease. Radionuclide activity in gliomas may be normal, decreased, or increased in the region of the tumor. In cerebrovascular occlusion, decreased activity, associated with a delay in time-to-peak activity, is frequently demonstrated in the affected hemisphere.