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Biomedical subjects

M S Islam

Publications and source records attributed to M S Islam.

At least 163 records · Page 9Linked to original sources

An outbreak of dysentery caused by Shigella dysenteriae type 1 on a coral island in the Bay of Bengal.

An epidemic of severe dysentery occurred on St. Martin Island in the Bay of Bengal at a time when the island, with a population of 1,318, was isolated from the mainland because of the monsoon season. There were 434 cases and 28 deaths within a three-month period. Mortality (2%) was limited to the very young and the elderly. Shigella dysenteriae type 1 (Shiga bacillus) was isolated from 12 of 65 rectal swab specimens. All strains gave similar biochemical reactions and were resistant to tetracycline, chloramphenicol, streptomycin, and the sulfonamides but were sensitive to ampicillin, kanamycin, and gentamicin. No other organism was implicated in the outbreak. The disease disappeared from the island after institution of chlorination of the sources of drinking water and effective treatment of patients.

Adolescent↗

[Local oversensitivity of sensoric receptors as cause of reflectoric airway obstruction (author's transl)].

The effect of local intratracheal, intrabronchial, and intravenous application of histamine, has been studied in dogs. Control studies are also carried out with saline. There is an increase in intrathoracic pressure per 100 ml of tidal volume due to locally applied histamine. This change is considered as the measure of bronchoconstriction. There is also a significant change in the bronchial sensitivity to acetylcholine inhalation. The intravenous application of the same quantity of histamine produces very little change in the bronchial sensitivity though it has produced strong and prolonged circulatory effect and even transitory respiratory arrest. The application of saline produces no change. It is concluded that the local chemical stimulus can sensitize the whole respiratory system and produces greater bronchconstriction involving some reflex path.

Acetylcholine↗