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Biomedical subjects

M S Devgun

Publications and source records attributed to M S Devgun.

24 records · Page 2Linked to original sources
PubMed1981

Vitamin and mineral nutrition in chronic alcoholics including patients with Korsakoff's psychosis.

1. A group of 129 patients with chronic alcoholism were assessed for their nutritional status with respect to certain minerals and vitamins, and compared with control subjects. 2. In all subjects the plasma values were normal for calcium, magnesium and zinc. 3. As in other studies a seasonal variation was found in the plasma levels of 25-hydroxyvitamin D in the control subjects and the alcoholic subjects; in all seasons lower levels were found in the alcoholics than in the controls, but none of the alcoholic patients had results in the range found in osteomalacia. 4. The alcoholic subjects had low levels of ascorbic acid both in the plasma and in the leucocytes. 5. Although vitamin A and beta-carotene levels were within the reference range, the results in alcoholics were found to be lower than in the control subjects. 6. We suggest that subclinical vitamin deficiencies other than thiamine deficiency contribute to the cerebral impairment frequently found in alcoholism.

25-Hydroxyvitamin D 2↗
PubMed1981

Vitamin D nutrition in relation to season and occupation.

Seasonal variations in vitamin D nutrition were assessed by measurements of serum 25-hydroxycholecalciferol levels in outdoor workers, indoor workers and long-term hospital inpatients. All three groups showed seasonal changes and the outdoor workers had, as might be expected, the highest levels at all seasons. However, the highest levels of 25-hydroxycholecalciferol were found in October in the indoor workers and in November for the outdoor workers whereas the peak in ultraviolet exposure was in July. The possible reasons for this long lag are discussed; the most likely explanation is that vitamin D continues to be formed and stored during the autumn especially in outdoor workers.

Adult↗
PubMed1981

Seasonal changes in the activity of serum alkaline phosphatase.

This paper reports a seasonal variation in alkaline phosphatase (ALP) levels in the serum, with low values occurring in summer and high in winter. These variations were found both in indoor and outdoor workers and in a group of elderly women in a long-stay ward. The seasonal change in ALP was in the opposite direction to the seasonal change in the serum levels of 25-hydroxyvitamin D. No such change was seen in the serum levels of gamma-glutamyltransferase. It is suggested that the seasonal change in plasma ALP could be due to changes in the bone isoenzyme. Serum levels of calcium remained unchanged; the change in ALP may reflect a homeostatic mechanism controlling plasma calcium, which compensates for seasonal variations in vitamin D supply.

25-Hydroxyvitamin D 2↗
PubMedDate not supplied

Effects of acute and varying amounts of alcohol consumption on alkaline phosphatase, aspartate transaminase, and gamma-glutamyltransferase.

Acute alcohol consumption has no effect on the levels of enzymes in serum. Regardless of the amount consumed, no significant changes in serum enzymes were observed. Age-related differences in gamma-glutamyltransferase were not apparent. Peak blood alcohol concentration and consumption are not related to the body mass. Screening of drunk drivers for detecting problem drinkers could be undertaken by performing biochemical measurements of serum enzymes, especially gamma-glutamyltransferase.

Adolescent↗