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Biomedical subjects

M S Bruno

Publications and source records attributed to M S Bruno.

At least 37 records · Page 2Linked to original sources

Transluminal coronary angioplasty during saphenous coronary bypass surgery: a preliminary report.

A previously described balloon tipped dilatation catheter has been used during revascularization surgery to dilate lesions which potentially could limit the runoff of the saphenous bypass grafts. A total of 34 lesions were dilated in 25 patients. Restudy of 12 patients (15 lesions) demonstrated positive results and no clinically significant complications. These preliminary results suggest an important role for transluminal coronary dilatation in the operative treatment of coronary artery disease.

Aged↗

Evaluation of a rechargeable pacemaker system.

A rechargeable-demand nickel-cadmium pulse generator for permanent transvenous cardiac pacing was evaluated in 66 patients. During a cumulative follow-up period of 2,333 patient months (194.4 patient years), failure of the pacing circuit occurred in 3 patients at 21, 25, and 27 months, respectively. Nine patients had difficulty accepting the recharging concept and, in 3 of these patients, it became necessary to replace the rechargeable generator with a conventional energy source. The overall failure rate of approximately 3% per year (including the 3 patients in whom it was necessary to remove the generator because of failure to recharge properly), coupled with the inconvenience of recharging, limits the usefulness of the rechargeable system compared to the newer lithium-powered generator.

Cadmium↗

Reduced incidence of intraoperative myocardial infarction during coronary bypass surgery with use of intracoronary shunt technique.

Intraoperative myocardial infarction is a recognized complication of aortocoronary bypass surgery. One major cause of such infarction may be interruption of coronary blood flow, particularly in patient with poor coronary collateral circulation. In 30 patients use of an intracoronary shunt made it possible to limit the period of coronary occulusion during graft construction to a few minutes. Use of this shunt was associated with a reduced incidence of intraoperative myocardial infarction (as judged by the appearance of new Q waves) when these patients were compared with 50 patients operated on without this procedure (6 of 50 [12 percent] versus 0 of 30). The incidence of postoperative persistent S-T segment elevation was reduced from 21 of 50 (42 percent) to 5 of 30 (17 percent). Except for use of the shunt, the surgical technique was identical in the two groups of patients.

Coronary Artery Bypass↗

Early evaluation of a rechargeable pacemaker system.

A rechargeable demand pulse generator for permanent transvenous cardiac pacing was evaluated in 66 patients. During a cumulative follow-up period of 895 patient months there was no instance of failure of either the pulse generator or of the recharging circuit. Acceptance of the recharging concept was high, there being only one patient in whom it was necessary to replace the rechargeable generator because of inability to master the recharging technique. The early findings indicate that with proper patient selection the rechargeable pulse generator promises to be an important contribution to pacemaker therapy.

Adult↗

Incidence and implications of abnormal intraventricular conduction in the coronary care unit.

A transient, intermittent, or permanent disorder of intraventricular conduction was found in 35% of 404 patients with acute myocardial infarction. Patients with acute myocardial infarction and abnormal intraventricular conduction were older than patients with normal intraventricular conduction, but there was no significant age difference between patients with normal and abnormal intraventricular conduction who died. Mortality was only slightly higher in patients with preexisting intraventricular conduction disorder than in patients with normal intraventricular conduction. On the other hand, mortality was remarkably higher in patients in whom abnormal intraventricular conduction developed during the course of acute myocardial infarction than in patients with either normal intraventricular conduction or preexisting abnormal intraventricular conduction. Transvenous cardiac pacing had little impact on mortality, death being due to pump failure in the majority of the patients. This study identifies a group of high-risk patients in whom early aggressive management utilizing newer therapeutic modalities such as mechanical circulatory assistance, emergency aortocoronary bypass, or both, might be profitably applied.

Acute Disease↗

Right ventricular apexangiography for precise placement of transvenous electrode catheters.

A simple angiographic technique (right ventricular apexangiography) for positioning permanent transvenous pacemakers is described. With this technique, electrode failure occurred in only five (3%) of 186 patients followed for more than two years, as compared to an average failure rate of 23% in 11 reported series. Right ventricular apexangiography should be particularly useful in those patients in whom problems arise during insertion of a permanent transvenous electrode catheter.

Cardiac Catheterization↗

Coronary arteriographic appearances in patients with left anterior hemiblock.

24 of 163 consecutive patients (14.7%) undergoing selective coronary arteriography were found to have electrocardiographic evidence of left anterior hemiblock. 3 patients (2 of whom had alcoholic cardiomyopathy) had normal coronary arteries, 15 patients had triple vessel disease, 3 patients had double vessel disease, and 3 patients had single vessel disease. 18 patients (75%) had moderate to severe left ventricular enlargement as estimated by left ventriculogram. Comparison of these angiographic findings with those of 88 patients with normal intraventricular conduction showed the distribution of the coronary artery disease to be essentially similar in the two groups but that significant left ventricular enlargement was at least three times more frequent in patients with left anterior hemiblock than in patients with normal intraventricular conduction. It is suggested that the development of left anterior hemiblock depends more upon the presence of left ventricular enlargement than on the distribution of the coronary artery disease.

Adult↗

"Cine" qua non.

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Angiocardiography↗