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Biomedical subjects

M S Bornman

Publications and source records attributed to M S Bornman.

At least 37 records · Page 2Linked to original sources

Trauma of the ureter.

Thirty-three ureteric injuries were treated over a 2-year period. The majority of patients presented late. The most common modes of repair were either ureteroneocystostomy or transuretero-ureterostomy. Complications were few and of little significance.

Adult↗

Comparative trial of sclerotherapy for hydroceles.

We present a prospective single-blind trial of sclerotherapy for hydroceles with tetradecyl sulphate and rolitetracycline as sclerosants. Twenty-seven hydroceles were treated with tetradecyl sulphate and 28 with rolitetracycline. The median follow-up was 13 months. There were no statistically significant differences between the 2 drugs in respect of cure rate and complications. The overall cure rate for both drugs was 96%. Complications were rare and common to both drugs. Tetradecyl sulphate and rolitetracycline were found to be equally effective as sclerosants.

Adolescent↗

Sclerotherapy for hydroceles.

Sclerotherapy with 3% sodium tetradecyl sulfate and 3.5% rolitetracycline on an outpatient basis was applied to 55 hydroceles. The over-all cure rate was 96% with an average followup of 13 months. Of the patients 64% were cured after only 1 sclerosant instillation. A post-sclerotherapy operation was necessary in 4% of the patients. Pain of a significant degree occurred after sclerotherapy in only 29% of the patients. Sclerotherapy appears to be an effective, economical and safe form of outpatient therapy for hydroceles.

Ambulatory Care↗

Seminal carnitine, epididymal function and spermatozoal motility.

The carnitine content of semen from azoospermic subjects and subjects with either impaired motility or forward progression is reported. Within the azoospermic group, the values were not significantly different between those with testicular failure or obstruction. The patients with impaired motility (less than 40%) or impaired forward progression (less than 3) had a lower mean seminal carnitine content than those with good motility and forward progression (P less than 0.05). Seminal carnitine concentration was not an index of epididymal patency and could not be regarded as useful for locating the level of obstruction in the epididymis. Since carnitine plays an important role in the maturation process when sperm acquire motility, it would seem that seminal carnitine might be an indicator of epididymal dysfunction.

Carnitine↗

The suppression of electro-ejaculation in the chacma baboon (Papio ursinus) by azaperone.

Six baboons (Papio ursinus) males were immobilised on five occasions at intervals of two weeks using a combination of ketamine hydrochloride and xylazine. The animals were subsequently successfully electro-ejaculated. No semen was obtained from animals when azaperone was used instead of xylazine, despite the use of a successful standardised method of electrical stimulation.

Animals↗

Quality of semen obtained by electroejaculation from chacma baboons (Papio ursinus).

Fifty-four baboons (Papio ursinus) were subjected to an electro-ejaculation procedure that yielded 683 usable ejaculates in 705 attempts. Quality evaluations by usual human spermiogram methods were applicable with only minor modifications to the procedures. By human criteria these wild baboons remained fertile after capture, and their use as a fertility model in pharmacological studies appeared to be appropriate.

Animals↗

Renographic comparison of function in bivalved kidneys repaired using either a fibrin adhesive (Tisseel) or conventional suturing.

In 6 male baboons, the left kidney was bivalved and repaired using a fibrin adhesive (group A) or conventional suturing (group B). 99mTc diethylenetriamine penta-acetic acid (DTPA) renography was used to evaluate renal function for up to 24 weeks after surgery. No significant impairment of renal function could be detected for either of the two repair methods. It seems as though the function was less affected after suturing, but the trend could not be supported statistically. The fibrin adhesive did not prove superior to conventional suturing.

Animals↗

Smoking and vascular impotence. A reason for concern.

Of the patients at an impotence clinic 39% were classified as having vasculogenic impotence. They were in a high age group and 93% smoked. The possible role of smoking in the pathogenesis of the impotence of ageing is discussed.

Adult↗

Entrapment of platelets in the penis during and after erection.

Because of the development of hypercoagulability and the deposition of fibrin in the penis during erection a study of the possible role of platelets in this process was undertaken. Platelet response was studied in 9 adult chacma baboons (Papio ursinus) using autologous in vitro indium-111-labelled platelets and sequential scintigraphy of the penis during erection. The blood pooling pattern was obtained using in vivo technetium-99m-labelled red cells in a similar investigation. A statistically significant retention of platelets occurred during and after erection, which could not be attributed to blood pooling (P less than 0,05). Entrapment of platelets could lead to enhanced activity and activation, and might play a significant role in hypercoagulability and fibrin deposition during erection. Therefore platelets could be an important factor in the pathogenesis of ageing impotence.

Animals↗

[Anomalies of the inferior vena cava. 2 case reports].

Two cases of anomalous inferior vena cava are presented, with the emphasis on embryology. The first patient was investigated by venography for a clinically proven varicocele as a probable cause of infertility. A double inferior vena cava was found during venography, and was confirmed by computed tomography (CT). In the second case a left-sided inferior vena cava was an incidental finding when a CT scan was done as a diagnostic procedure in a case of Hodgkin's disease. A short summary of the embryology and the significance of the variants is presented.

Adult↗