Biomedical subjects
Publications and source records attributed to M S Bogle.
Eccrine differentiation according to histologic and immunohistochemical criteria was demonstrated in 16 of 66 basal cell carcinomas. The possibility of origin of these neoplasms from the eccrine duct, including the acrosyringium, is discussed in relation to the differences in site distribution and etiology between basal cell carcinoma and squamous cell carcinoma.
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Twenty-three children with primary obstructive megaureters presented between 1978 and 1988 to the Princess Margaret Hospital for Children in Perth. Twenty-eight ureters were treated. Urinary infections were the presenting feature in 14 children. The obstructive segment was transvesically excised. Histopathologic examination of the distal, intramural ureter showed fibromuscular disarray with a relative increase in fibrous tissue and reduction of musculature in all specimens. Twenty-two ureters were tapered by excision and all 28 were reimplanted using an antireflux technique. Seventeen children were followed for an average of 3 years. Seven children showed renal growth, reduction in ureteric size by greater than 2 cm, improvement in glomerular filtration rate by more than 10%, no obstruction on reflux, and no infections in postoperative period. Four children showed all the above but suffered one or more infections after the operation. Of the remaining 6 children, 3 had postoperative obstruction and 3 had vesicoureteric reflux.