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Biomedical subjects

M Rubin

Publications and source records attributed to M Rubin.

At least 199 records · Page 11Linked to original sources

The day hospital as entry point to a network of long-term services: a program evaluation.

One hundred twenty-six admissions to a time-limited day hospital program were studied to obtain evaluative and descriptive information about the program and its patients. Patients most likely to complete the program were older, lived with their families, had intermediate amounts of prior inpatient admissions, and had no arrest record. Among all study patients admitted to the day hospital (dropouts as well as graduates), 62 percent were still participating in at least one long-term treatment and rehabilitation program of the parent community mental health service six months after they left the day hospital. This high retention rate appears to result from the day hospital's focus as the entry point to a large and flexible network of long-term services in the same location and with familiar staff.

Adult↗

[Dermatoses in the metallurgy industry].

The authors proceeded to a skin examination of 1,194 consecutive workers in a cutlery industry with 3,692 employees, in order to detect any cutaneous alterations among them. Only 223 (18.7%) had no skin pathology. Most of them, 971 (81.3%) presented some cutaneous disorder, related or not with their work. Hyperkeratosis of the fingers and hands (262 cases) caused by repeated traumas due to the manipulation of the instruments of work were the most noticeable and specific occupational skin alteration. In second place in order of frequency were the intertriginous mycotic inflammation of the toes: 255 cases. The authors call attention to the low incidence of the sexually transmitted diseases as well as of scabies, pediculosis and impetigo.

Adolescent↗

The effect of an aerosolized antihistamine, chlorpheniramine maleate, on exercise-induced bronchospasm.

We studied the effect on airway function of chlorpheniramine maleate (C), an H1 antagonist, delivered as an aerosol to 12 asthmatic subjects, 40 minutes before submaximal exercise. The study consisted of three protocol days. A first day established that the asthmatic subjects had exercise-induced bronchospasm (EIB). On the remaining two protocol days, 10 mg of C or a saline placebo (P) were administered by aerosol nebulizer in a double-blind randomized fashion over a 5-minute period. Pulmonary function was measured immediately after the aerosol inhalation as well as 10 and 30 minutes later. A 5-7-minute period of exercise was then performed by each subject on a cycloergometer, and lung function was again measured immediately and 5 minutes after exercise. Thirty minutes after the inhalation of C there was a significant increase in lung function parameters (1.80 +/- 0.23 to 2.32 +/- 0.34/sec for MEF40%(P); Mean +/- 1 SE, P less than .05) but not for placebo. MEF40%(P) remained significantly higher on the C day than on the P day following exercise; however, this difference was no greater than the difference seen immediately before exercise. We suggest that C promotes mild bronchodilation of asthmatic airways, and that this effect in EIB may be interpreted as the result of an alteration of baseline airway caliber.

Adult↗

Percutaneous brachial catheterization using a modified sheath and new catheter system.

An alternative method for left heart catheterization via the brachial artery, without cutdown, is described. Percutaneous brachial catheterization was done with a modified 7F side-arm sheath with check valve. A modified 7F high flow catheter was developed employing characteristics of both multipurpose and Sones catheters. The technique was used in 100 patients for left heart catheterization, in patients with and without aortic valve disease, for left ventricular angiography and selective coronary angiography. There were no failures or serious complications. All puncture sites were managed with 15-20 minutes of compression using only a blood pressure cuff or finger pressure. Bleeding was controlled with restoration of the radial pulse in all but one patient, who had severe peripheral brachial atherosclerosis. Cutdown and thrombectomy performed before he left the laboratory using standard catheterization techniques promptly restored blood flow. It is our impression that this technique facilitated outpatient catheterizations, repeat catheterizations at sites of previous cutdowns, and reduced patient discomfort.

Adult↗

Gastric carcinoid: two unusual presentations.

We report two cases of gastric carcinoid that presented as benign-appearing polyps. One presented with multiple, benign-appearing polyps--a particularly unusual presentation for an uncommon tumor. The second patient had a single polypoid gastric carcinoid and atropic gastritis with pernicious anemia. These atypical presentations and uncommon association of gastric carcinoid are discussed.

Adult↗

Mild cervical dysplasia. Experience in a family planning clinic.

To evaluate mild cervical dysplasia, the results of Papanicolaou smears were reviewed for a six-month period in an inner-city family planning program. Papanicolaou smear evidence of mild dysplasia was consistent with the biopsy diagnosis in most cases. A single Papanicolaou smear is not a reliable indication of condylomata, nor is a single normal Papanicolaou smear in this setting completely reassuring. Persistent mild dysplasia is an indicator of high risk for cervical dysplasia and cervical infection. Aggressive initial cervical surgery is not indicated, but close follow-up is required.

Adolescent↗

Intraoperative Gram's staining of bile as a guide for early selective administration of antibiotics.

A prospective clinicobacteriological study was undertaken in 100 patients undergoing biliary surgery, to assess the influence on the postoperative course of early antibiotic treatment that was instituted in accordance with the results of intraoperative Gram's staining of gallbladder bile. The wound infection rate was found to be 9% and there wee no other septic complications. The sensitivity of Gram's staining as compared with the results of bile cultures was found to be 65.5%. This study provides additional evidence of the value of Gram's staining of bile as a means for the early discovery of pathogens and early institution of antibiotic therapy, both important factors in lowering the rate of infective postoperative complications.

Adult↗

Regional enteritis with major gastrointestinal hemorrhage as the initial manifestation.

Four patients with massive gastrointestinal hemorrhage were found to have Crohn's ileitis. This prompted a five-year chart review of consecutive admissions for Crohn's enteritis; 60 patients were found whose disease was limited to the distal part of the ileum (and rarely the proximal part of the cecum). Eight (13%) of these patients were admitted because of major rectal bleeding, and in seven of the eight the hemorrhage was the initial manifestation of Crohn's disease. The mean age of the entire group was 30 years, with a mean age of 18.6 years in the eight bleeders. Crohn's ileitis should be considered in the differential diagnosis of massive rectal bleeding, especially in younger patients.

Adolescent↗

Cronkhite-Canada syndrome: report of an unusual case.

This report describes the findings in a 58-yr-old woman with multiple gastrointestinal polyps, associated with diarrhea, abdominal discomfort, hypoalbuminemia, alopecia, nail atrophy, and pigmentary changes. The patient met the criteria of the Cronkhite-Canada syndrome. Pathological evaluation of her polyps revealed regenerative (inflammatory) pseudopolyps, rather than true adenomatous polyps recorded in some earlier descriptions of patients with this syndrome. This is the first report of the association of Cronkhite-Canada syndrome with multiple myeloma.

Alopecia↗