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Biomedical subjects

M Rossetti

Publications and source records attributed to M Rossetti.

At least 73 records · Page 4Linked to original sources

The impact of non-physician health directors on full-time public health coverage in Connecticut.

Seven years after passing a 1971 law enabling individuals without MD degrees but trained in public health to become local directors of health, the proportion of Connecticut towns covered by full-time directors had risen from 14 per cent to 38 per cent and the proportion of the population covered had risen from 46 per cent to 63 per cent. The directors of health without MD degrees were satisfied with their positions and believed they had developed good relationships with physicians, the community, and government.

Connecticut↗

[Anastomoses in intestinal surgery (author's transl)].

Prerequisites for anastomoses in intestinal surgery are: 1. no tension on the suture line, 2. preservation of vascularity, 3. cut bowel ends without malignant or severe inflammatory disease. Healing is influenced by general conditions, operative technique, kind and strength of suture material, number of sutures and layers and so on. Usually, a one step procedure with end-on single layer anastomosis is recommended.

Humans↗

[Long-term results of thoracic truncal vagotomy and pyloroplasty in complicated reflux disease].

In advanced cases of esophagitis with acquired short esophagus and stricture, operative treatment to eliminate gastroesophageal reflux may be difficult or impossible. 24 such patients were treated by transthoracic truncal vagotomy and pyloroplasty. In a long-term follow-up 9--11 years later 12 patients were examined by X-ray and esophagoscopy. In 9 patients symptoms due to reflux or obstruction had improved, 5 of them were symptom-free. At endoscopy and barium-swallow 2 patients showed back-formation of their stricture, the other patients had generally unchanged findings. Transthoracic truncal vagotomy with drainage seems to be able to prevent progression of severe esophagitis and to improve its symptoms.

Esophageal Stenosis↗

[Adenocarcinoma of the thoracic esophagus in reflux disease].

Organic reflux disease is a pre-cancerous state. Adenocarcinoma characterized by aggressive growth, poor prognosis, rapid lymphatic and haematological spread and a technically challenging operation were found to develop in the middle or distal third of the oesophagus in 26 of a series of 262 cases (endobrachyoesophagus, grade 2 reflux oesophagitis). Only 7 of the 26 were operable of whom only 2 survived for 2--3 years. This stresses the importance of clear guidelines for a timely operation in lessening the danger of the evolving reflux disease. Comprehensive long-term controls are necessary to know whether surgery aimed at impeding the reflux element has been successful.

Adenocarcinoma↗

[Intestinal endometriosis as a surgical problem].

6 cases of colonic endometriosis, treated by surgery, are presented. The average age was 50 years. All patients also had concomitant genital endometriosis and 5 of these 6 women have had previous pregnancies. Pathological findings were intramural colonic growth leading to stenosis and tumor like endometriomas. 3 times a sigma resection, once an ileo-cecal and once an anterior resection was carried out, there is in one instancy the stenosis could be overcome by enucleation. Postoperative course was uneventful, but one case later on developed a rectal carcinoma--first mistaken as recurrence of intestinal endometriosis.

Colonic Neoplasms↗

[Effect of polyunsaturated fatty acids on experimental ulcer in the rat].

The increase of gastric mucosal defensive reachons under linoleic acid loading (20 mg/kg i.m. x 2 x 10 die; 140-220 mg/kg per os x 2 x 15 die), was evaluated in hydrocortisone treated rats (10 mg/kg i.m. x 2 x 10 die) and in rats stressed by immobilisation at a low temperature (at 4 degrees for 1 hour). The incidence and extent of gastric lesions were recorded, in both samples treated differentialy, and in control groups. Although the results were not similarly significant in every case, the capacity of the linoleic acid administrations in limiting the gastric mucose injury was evident. This protective capacity is not dependent on the lesive agent.

Animals↗

[60 cases of stenosis of the thoracic esophagus. Surgical technic].

Thoracic esophageal stenosis most frequently is seen in reflux disease as sequelae of endobrachyesophagus. In 10% of these cases later on an adenocarcinoma will be proven. Of special therapeutic interest in this field is the relationship with the Zollinger-Ellison syndrome, with scleroderma and with juvenile acid burns of the esophagus. As operative therapy in the benign state of reflux disease we advise conservative, organ-preserving, functional surgery with peroperative dilatation, abdominal fundoplication and, if necessary, vagotomy. Long-term follow-up results are demonstrated.

Adenocarcinoma↗

[Rectosigmoidovesical fistula].

The symptomatology of vesico-colonic fistulae is presented and their differential diagnosis discussed. Management should be tailored to the individual case. Whenever possible, we perform a radical primary operation. An additional by-pass colostomy is indicated if it is felt that the integrity of the anastomosis is jeopardised.

Colon, Sigmoid↗

[Does every hospital need a catastrophe plan?].

The organisation of any hospital to manage the medical supply in case of general disaster should guarantee the maximum effectiveness. The increase of output has to be realised on the emergency ward, OR, JCU and on the general wards. The planning should include the management, the competence and the coordination inside and outside the hospital.

Disaster Planning↗