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Biomedical subjects

M Rosol

Publications and source records attributed to M Rosol.

At least 19 recordsLinked to original sources

[Studies on the increase in the incidence of endometrial and ovarian in cancer in Czechoslovakia during 1960-1973].

During the time period of the last 12 years the incidence of the endometrium carcinoma in the whole CSSR rised to 155,5% in the consideration of the incidence in the years 1961 to 1963. In the same time period the incidence of the ovarial carcinoma has grown up to 117,8% only, what seems to be still in the limits of average incidence shift of all female malignancies in the CSSR (117,1%). The rising incidence of endometrium carcinoma affects primarily the elderly women, but testiefies also that this malignancy is among them today much more frequent. Therefore the rising incidence cannot be explained only as a manifestation of elderly of the female population. In agreement with this reality the endometrium carcinoma is today diagnosed significantly more frequently also among the younger women (at least since 40 years of age). The totals of all endometrium carcinomas rised even more than incidence. The gynaecologists meet today 162% of such malignancies in comparison with the numbers in the years 1961-1963. It means that in the whole CSSR yearly 500 endometrium carcinomas more are diagnosed than before 12 years. The incidence of cervix carcinoma dropped during the same period significantly and the endometrium carcinoma became therefore nearly as frequent as cervical malignancy (1:1,2). Possible reasons of these frequency changes are discussed.

Adult

[Precancerous conditions in the cervix uteri in young women].

The author presents the increasing securing of various degrees of atypiae of the epithelium in the uterine neck including carcinoma in situ, and even carcinoma invasivum in young females in connection with preventive examinations being extended even on young females without age limit. In the years 1961 to 1973 only in the district Hradec Králové and its environment, a total of 181 females with a pathological finding in the cervix was found. Out of them in 19 females carcinoma in situ with with the onset of invasion was observed, in 13 females progressive carcinoma invasivum was found. Mutual relations are shown in Table I and Table II. In Table III the author wants to show that all preventive examinations in all females coming to the prenatal consulting centre for the first time are worth being carried out thoroughly. Thus 51 females--very young--with a finding in the cervix were discovered. The performance of preventive examinations as late as after the thirtieth year of age is considered to be incorrect. When searching for precanceroses of the uterine neck it is not possible to state any limits. The sooner and the more frequent the prebioptic examination methods are employed, the more probably the changes which may be, however, reversible, but which never exclude any possibility of malignant development may be found.

Adolescent