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Biomedical subjects

M Rose

Publications and source records attributed to M Rose.

At least 271 records · Page 15Linked to original sources
PubMed1976

Effects of intravenous glucose during pacing-induced angina pectoris in patients with coronary artery disease.

The effects of hypertonic glucose infusion on the anginal threshold determined by atrial pacing was studied in 14 patients with significant coronary artery disease. After glucose, angina occurred at a significantly lower heart rate and double product (systolic arterial pressure x heart rate), suggesting a decreased tolerance to ischemic stress. No stoichiometric relationship was noted between glucose uptake and lactate production, and there was no evidence that hypertonic glucose infusion resulted in enhanced anaerobic glycolysis in the ischemic myocardium. Acute elevation of plasma glucose levels may not be beneficial to patients with coronary artery disease.

Anaerobiosis↗
PubMed1976

The influence of duration of circulatory arrest at 20 degrees C on cerebral changes.

In infants and piglets subjected to periods of circulatory arrest at 20 degrees C there was close correlation between duration of arrest and delay in return of electroencephalographic activity. Post mortem studies demonstrated histological evidence of brain damage in patients after circulatory arrest at 20 degrees C. Similar histological changes were demonstrated in piglets, including some who had complete E.E.G. and clinical recovery from circulatory arrest.

Animals↗
PubMed1976

Intravitreal antibiotic injection and vitrectomy in acute bacterial endophthalmitis.

Two days after an unplanned extra-capsular cataract extraction with sector iridectomy, a patient showed typical signs of bacterial endophthalmitis. Vitreous and aqueous were aspirated for culture, and gentamicin and dexamethasone were injected. Twenty-four hours later, after isolation of Staphylococcus epidermidis, a vitrectomy to remove the central vitreous was done. Postoperatively, vision progressively improved; at the last review nine months after vitrectomy, visual acuity was 20/50.

Anterior Chamber↗
PubMed1975

The vitrophage in ocular trauma. Report of 15 cases.

Fifteen patients underwent a pars plana approach vitrectomy and membranectomy after acute and chronic injury. In all cases the lens fragments, hemorrhage, and secondary membranes were removed restoring clarity to the ocular media. In two cases the final visual acuity was limited by preexisting retinal injury. The advantages of pars plana approach are the small incision and minimal ocular manipulation during surgery. In the presence of retinal injury, diathermy during the procedure or photocoagulation within 24 hours is also indicated.

Acute Disease↗
PubMed1975

Management of traumatic retinal detachment with pars plana vitrectomy, scleral buckling, and gas injection.

Vitreous involvement as a result of penetrating trauma complicates and worsens the prognosis in retinal detachment repair. Seven patients in whom poor visualization of the fundus seemed to preclude success by routine procedures underwent combined vitrectomy, scleral buckling, release of subretinal fluid, and intravitreal gas injection. The retina was successfully reattached in five of the seven patients, although postoperative visual acuity was limited - possible on account of the duration of retinal detachment prior to repair or because of the degree of macular involvement.

Adolescent↗