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Biomedical subjects

M Rosati

Publications and source records attributed to M Rosati.

At least 37 records · Page 2Linked to original sources
PubMed1995

Persistent median artery in carpal tunnel syndrome.

Persistent median artery of the forearm and wrist is not very frequently observed. Only a few cases of persistent median artery thrombosis associated with compression of the median nerve in the carpal tunnel have been reported: in these cases symptoms arise acutely and surgery consists in the excision of the thrombosed arterial branch. In a patient with recurrent carpal tunnel syndrome, with a patent median artery and duplication of the median nerve, we performed neurolysis of the nerve and repositioning of the artery to the ulnar side. Electromyography, arteriography and clinical examinations performed six months later showed that irritative phenomena of the median nerve had regressed and the artery was still patent.

Adult↗
PubMed1994

Endoscopic treatment of dermoid cyst.

Seven cases of benign cystic teratoma (dermoid cyst) were managed laparoscopically (six cyst excisions and one adnexectomy) using a surgical procedure to avoid spillage. Outcome was good in all cases without any complications.

Adult↗
PubMed1993

A novel X-linked member of the human zinc finger protein gene family: isolation, mapping, and expression.

We report the partial characterization of a novel putative zinc finger gene of the Krüppel-type (ZNF81), isolated from an X Chromosome (Chr) specific library. The pattern of segregation in human-hamster somatic cell hybrids of sequences homologous to the ZNF81 finger domain has established that it resides within the Xp22.1-Xp11 region. ZNF81 represents yet another example, together with ZFX, ZNF41, and ZNF21, of members of the zinc finger gene family residing within the short arm of the human X Chr. Sequence analysis showed that ZNF81 may encode a polypeptide(s) containing tandem arrays of 12 canonical C2H2 zinc fingers of the Krüppel-type at the C-terminus. Northern analysis indicated that probes from the ZNF81 finger domain hybridize to polyadenylated transcripts present in several cell lines, a result that supports the hypothesis that it is an expressed, functional member of this multigene family.

Amino Acid Sequence↗
PubMed1993

[Not Available].

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Eye Diseases↗
PubMed1991

Members of the zinc finger protein gene family sharing a conserved N-terminal module.

We report the isolation of human members of a sub-family of structurally related finger protein genes. These potentially encode polypeptides containing finger motifs of the Krüppel type at the C-terminus, and a conserved amino acid module at the N-terminus; because of its invariant location the latter is referred to as finger preceding box (FPB). The FPB, detected also in previously described finger proteins from human, mouse and Xenopus, extends over approximately 65 amino acids and appears to be composed of two contiguous modules: FPB-A (residues 1-42) and FPB-B (residues 43-65). The latter is absent in some of the members analyzed. Elements A and B and the zinc finger domain are encoded by separate exons in the ZNF2 gene, a human member of this sub-family. The positioning of introns within this gene is remarkable. One intron flanks and a second interrupts the first codon of the FPB-A and FPB-B modules, respectively. A third intron occurs a few nucleotides downstream of FPB-B marking its separation from the remainder of the coding sequences. This organization, together with the absence of FPB-B in some cDNAs, supports the hypothesis that mRNAs encoding polypeptides that include one, both or none of the FPB-A and FPB-B modules may be assembled through alternative splicing pathways. Northern analyses showed that members of this sub-family are expressed as multiple transcripts in several cell lines. The sequences of distinct cDNAs homologous to the ZNF2 gene indicate that alternative splicing events adjoin either coding or non coding exons to the FPB sequences.

Amino Acid Sequence↗