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Biomedical subjects

M Rosa

Publications and source records attributed to M Rosa.

At least 73 records · Page 4Linked to original sources
PubMed1983

Influence of bromocriptine on glucose-3-H3 metabolism in vivo.

The dopaminergic agonist Bromocriptine has been perfused in vivo in normal Wistar rats to control its activity on Glucose-3-H3 metabolism. Bromocriptine shows a rapid influence on glucose production rate (Ra) and glucose utilization rate (Rd). Both rates increase, but since Bromocriptine effects on glucose production rate is more significant than the ones on glucose utilization, the final results is an increase in plasma glucose levels. Since glucose production rate in normal animals is practically equal to hepatic glucose output, the most logical explantation of Bromocriptine activity is the activation of glycogenosis with a rise of plasma glucose levels.

Animals↗
PubMed1983

The effects of a load of phenĭlalanine on glucose metabolism.

The clinical and experimental hyperphenylalaninemic conditions seem associated with disorders of carbohydrates metabolism. Examples are the increased liver glucose turnover and the glycogen depletion under Phenylalanine load and the hyperexcretion of glucose in the urine of PKU children. We studied the effects of an acute load of Phenylalanine on Glucose-3-H3 kinetics and plasma glucose levels in adult male Wistar rats. The effects of the load were very slow and after 40 minutes we observed an increase in the rate of plasma glucose production (Ra), that in normal animals in an almost exclusive liver function. As result of this glucose production there was a modest increase in plasma glucose levels.

Animals↗
PubMed1983

Degenerative changes in hypophyseal adenomas: CT features.

16 patients with hypophyseal adenoma undergoing degenerative changes, namely necrotic-cystic changes, bleeding and calcification, were subjected to CT and the resulting density values studied. The cases were verified at operation and at histological examination. Evaluation of these features, despite the limitations of the method, proved to be very useful in differential diagnosis and in the planning of treatment.

Adenoma↗
PubMed1983

Mellituria screening in some metabolic diseases.

Mellituria was studied in 83 subjects: 25 normal adults and children and 58 patients with several metabolic diseases. In comparison to the controls, no significant differences were found in 9 patients with cystinuria and in 2 patients with Apert's syndrome. The large excretion of glucose was the only important pattern of the 11 patients with insulin-dependent diabetes. In 23 patients with porphyria cutanea tarda a statistically significant increase in the excretion of pentose was observed. In 16 children with the classical form of phenylketonuria, a significant hypoexcretion of glucose was found. This latter observation could be explained by the carbohydrate metabolic alterations described in experimental hyperphenylalaninemia.

Abnormalities, Multiple↗
PubMed1982

Effects of an antiprostaglandin drug on human fallopian tubes in vivo.

The Authors studied 17 patients with patent tubes, normal ovulation and Rubin's test results. In the following cycle, this test was repeated divided into two phases. The first followed the normal procedure; the second started 10' after the e.v. administration of 50 mg of an antiprostaglandin drug (Ketoprophen). The results highlighted the capability of this drug to alter the activity of human tubes. A general increase was observed in the amplitude and frequency of tubal contractions. The Authors finally analyse the possible clinical use of this drug in the treatment of the tubal pathology.

Adult↗
PubMed1980

[Effects of sodium salicylate on blood sugar].

The effect of constant perfusion of sodium salicylate on blood glucose has been studied in anestethyzed normale Wistar rats. The sodium salicylate perfused at the rate of 0,148 mg/min for 30 minutes has not statistically significant effect on glycemia.

Animals↗
PubMed1980

[Metabolism of glucose-3-H3 during perfusion of sodium salicylate].

The effect of sodium salicylate perfused at constant rate for 30 minutes on Glucose-3-H3 kinetics has been studied in anestethyzed normal Wistar rats, controlling blood glucose levels, Ra and Rd. While blood glucose levels and Rd were not affected, the Ra values were influenced between the 20th and the 30th minute of salicylate perfusion.

Animals↗
PubMed1980

[Free carbohydrates of the normal liver].

A separation of liver carbohydrates was carried by means of paper chromatography on deproteinized ethanolic extracts of frozen livers. The carbohydrates most frequently observed were Ribose, Xylose, Fructose, Glucose, Maltose, Maltotriose, Maltotetrose; isomaltose was found less frequently.

Animals↗
PubMed1979

[The action of cyclic somatostatin on hypoglycemia due to prolonged fasting in normal animals].

The authors have examined the action of cyclic Somatostatin on blood glucose levels in normal rats and in rats starved for 36 and 50 hours. The infusion of 0,235 gamma/min. of Somatostatin for thirty minutes in the normals induced a slight increase in blood glucose levels that was statistically non significative. Under the same condition, the cyclic Somatostatin increased, in a statistically significant way, the levels of plasma glucose in both starved groups of rats.

Animals↗
PubMed1979

[Paper chromatography of the urinary carbohydrates in normal subjects: the aldoses].

The authors describe a method that utilizes paper chromatography for the separation and identification of urinary carbohydrates, especially the Aldoses. Using 5 ml. of urinary extract, it is possible to separate Lactose, Maltose, Galactose, Glucose, Fructose, Mannose + Arabinose, Xilose + Ribose, Glucuronolactone and other unidentified compounds.

Aldehydes↗