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Biomedical subjects

M Rivera

Publications and source records attributed to M Rivera.

At least 199 records · Page 11Linked to original sources
PubMed1983

Propranolol as a novel, effective spermicide: preliminary findings.

The efficacy and tolerability of 80 mg propranolol tablets as a vaginal contraceptive were studied in 198 fertile women for 11 months. The calculated one year life table pregnancy rate was 3.4/100 women and the Pearl index was 3.9/100 women years. No major adverse effects were encountered. The findings suggested that propranolol is an effective vaginal contraceptive whose failure rate compares favourably with that of other methods of contraception. Further study of propranolol and similar compounds is warranted.

Adolescent↗
PubMed1983

Single catheter technique for accurate cardiac outputs from left ventricle.

We report our experience in cardiac output measurements using a single catheter for left ventricular green dye injection with sampling from the side arm of a femoral artery introducer sheath. This technique is compared to thermal dilution (20 patients) and pulmonary artery green dye injection (20 patients). There were no significant differences between the single catheter left ventricular method and the other two accepted methods for measuring cardiac output.

Cardiac Catheterization↗
PubMed1982

Pseudomonas aeruginosa mucoid strain. Its significance in adult chest diseases.

Isolation of mucoid strains of Pseudomonas aeruginosa from bronchial secretions has occurred usually in the setting of cystic fibrosis. This association has been so strong that it is considered a sign of the presence of cystic fibrosis. We reviewed the records of 31 patients in whom this strain was isolated; in contract to previous experiences, we found that only 2 of our patients could be considered to have cystic fibrosis. The remainder all had a chronic pulmonary disease, and common to all was the presence of bronchiectasis. We conclude that isolation of mucoid strains of Pseudomonas aeruginosa from bronchial secretions of adults with a chronic pulmonary process indicates the presence of underlying bronchiectasis.

Adolescent↗
PubMed1982

Antibiotic therapy of acute exacerbations of chronic bronchitis. A controlled study using tetracycline.

We conducted a double-blind, randomized, placebo-controlled trial in 40 patients to evaluate the need for antibiotics in acute exacerbations of chronic bronchitis. All patients were sufficiently ill to require hospitalization although none needed ventilatory support; the presence of pneumonia was excluded. Treatment consisted of bronchodilators, corticosteroids, and either tetracycline, 500 mg, or placebo by mouth every 6 hours for 1 week. Arterial blood gases, spirometric tests, bacteriologic evaluation of sputum, and patient and physician evaluation of the severity of illness were assessed at the beginning and end of the study. All patients improved both symptomatically and by objective measures of lung function. At the end of the study period there were no differences between those patients receiving tetracycline and those receiving placebo. We conclude that antibiotic therapy is not needed in moderately ill patients with exacerbations of chronic bronchitis.

Acute Disease↗
PubMed1981

Trimellitic anhydride Toxicity. A cause of acute multisystem failure.

A person exposed to trimellitic anhydride (TMA) an epoxy resin widely used in industry, experienced respiratory failure, anemia, and gastrointestinal bleeding. A lung biopsy specimen demonstrated intra-alveolar hemorrhage and damage to alveolar lining cells. The patient and six co-workers were examined. Results indicated the presence of hemolytic antibodies directed against TMA-haptenized erythrocytes, IgG, IgA, and IgM antibodies directed against TMA-erythrocyte complexes, and antibodies against TMA-human serum albumin. Antibody levels in the patient were greater than in the co-workers. The elevated antibody levels demonstrate the antigenic potential of TMA. However, the cause of the pulmonary and hematologic damage remains uncertain and may represent either immunologic or direct toxic effects of TMA. In patients with multisystem failure of this nature, occupational hazards should be added to the differential diagnosis.

Adult↗
PubMed1981

Placidyl abuse: a dimorphic picture.

Eleven patients with documented intoxication with ethchlorvynol were evaluated for clinical and laboratory manifestations. All of the 7 patients who ingested the drug were severity neurologically depressed; 3 were hemodynamically unstable and 1 developed pulmonary edema documented to be noncardiogenic 40 h after admission. All of the remaining patients (including 1 who also ingested a small amount) presented with pulmonary edema in the absence of neurological changes, soon after injection of 2--3 capsules iv; hemodynamic measurements in one of these demonstrated a noncardiogenic etiology. The clinical manifestations in these 2 groups of patients seem to be clearly separable, depending on the dose and route of administration.

Adult↗
PubMed1981

Tricyclic antidepressant overdose: clinical and pharmacologic observations.

Forty-seven patients with confirmed TCA overdoses were thoroughly evaluated with regard to clinical and electrocardiographic findings. In 22 patients plasma levels of the primary TCA and the desmethyl metabolite were determined. We found that both neurologic and cardiovascular complications were common, but independent of each other. While plasma levels of the parent of TCA compound correlated best with the neurologic disturbances, cardiac abnormalities were more related to the desmethyl metabolite level. Although plasma levels correlate with the clinical findings, sufficient overlap between normal and abnormal levels and findings exist that we do not feel that routine measurement of plasma levels is clinically useful at this time.

Adult↗
PubMed1980

Unusual radiographic findings in adult pulmonary tuberculosis.

To determine the frequency of unusual chest radiographic findings in adults (older than 15 years) with pulmonary tuberculosis, charts and radiographs of 270 consecutive cases seen in a 12 month period were reviewed. Radiographic findings not typical of primary or postprimary disease (reinfection) were arbitrarily classified as unusual. The incidence of such findings (8%) was considerably lower than in several recent reports (25%, 29%). Likewise, the incidence of lower lobe tuberculosis in diabetics in this population (8.3%) was lower than in a report by Weaver (20%), and the finding of air-fluid levels in patients with cavitary disease (9%) was lower than a report by Cohen (22%). Possible explanations for these discrepancies were reviewed, including: (1) demographic characteristics, (2) the patient selection process, (3) the arbitrary nature of any system of classification of "unusual" findings, and (4) the change in the epidemiology of the disease as a result of chemotherapy and organized eradication programs. Of these, the patient selection process is probably the most significant factor in the discrepancy between the incidence of unusual findings in this series compared with those reported by others.

Adult↗
PubMed1979

Timing of the IUD insertion.

The relationship between the time in the menstrual cycle when a TCu-200 or Cu-7-200 is inserted and subsequent IUD-related events was evaluated. For women who had either TCus or Cu-7s inserted, the pregnancy, expulsion and medical removal rates were similar for insertions performed at any time of the menstrual cycle.

Aging↗