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Biomedical subjects

M Rieu

Publications and source records attributed to M Rieu.

126 records · Page 7Linked to original sources
PubMedDate not supplied

[Thyroid function of burned patients: effect of iodine therapy].

Thyroid function was studied in 3 groups of adults (group I = 13 burned patients treated with non iodinated antiseptic, group II = 15 burned patients treated with polyvidone iodine, group III = 50 control subjects) in order to examine: the thyroid hormone status in burned patients, the possible incidence of plasma iodine overload on these endocrine parameters. Burned skin area and thyroid function were measured before treatment, then weekly for 3 weeks. Before treatment a decrease in plasma T4 and T3 with an increase in reverse T3 (rT3) and a decrease in plasma thyroxin binding globulin (TBG) were observed in burned patients. Free T4 index (T4/TBG) was normal, but T3 resin uptake (T3RU) was elevated. During treatment, plasma iodine increase sharply from 6.4 +/- 0.4 to 20.7 +/- 4.7 micrograms/100 ml (p less than 0.02) in group II. Endocrine parameters (not different between group I and II) progressively returned to normal, except for T3RU which remained elevated until the third week. rT3, T4 and T3RU correlated (p less than 0.001) with burned skin area. To conclude, the reversible particularities of thyroid function in burned patients are positively correlated with burned area. The thyroid function does not seen to be modified by plasma iodine overload.

Adolescent↗
PubMedDate not supplied

[Hormone reactions to physical exercise following altitude training (author's transl)].

A three weeks physical training program at medium altitude induces some fonctional metabolic and hormonal changes in the response to physical effort. These changes vary, depending on whether the effort occurs on the 3rd or 7th day following return to sea-level. In the former case one observes a decrease in the somatotrophic response whereas in the latter one observes a decrease both in the somatotrophic and glucocorticoide response as well as in the level of blood contained lactic acids. These changes could be related to an improvement in the aerobic metabolism.

Adult↗
PubMedDate not supplied

[New light on the discussion about the therapeutic attitude during the first 72 hours in subjects highly burned. Study of 100 patients burned on 30 p. cent of body surface or more (author's transl)].

The quantity of given fluids was guided by the Evans rule but with no limitations of infusion above 50 p. cent of burns. Fluid was concentrated human serum albumine made isotonic by infusion through a Y pathway with 5 p. cent glucose, natrium (6 g/l) and carbo-hydrate for caloric needs. Under these conditions, clinical and biological parameters show the keeping of a good hemodynamic and hydroelectrolytic balance, with a level of blood proteins very near of the normal one, and a raise in body weight much lower than usually described in literature. Beyond this, the time needed to lower the body weight to its initial level is short and the quantity of infused liquid is much lower than that requisited by resuscitation utilising only cristalloid fluids for the first 24 hours.

Acid-Base Equilibrium↗
PubMedDate not supplied

[Evolution of blood fatty acid levels in severe burns].

During the first ten days following the burn, there is no significant increase in serum FFA for the surviving patients. This shows a good balance between production and use by the cells. The glucose that is brought allows their oxydation in tricarboxylic Kreb's cycle and the albumine allows for them transport in the circulating liquids, probably helping to maintain this good balance. On the other hand for 70 p. 100 of the patients who died this equilibrium does not exist and the serum FFA increased significantly. Later on and in all cases, the value of serum FFA decrease significantly below that of the control group. This fact can be explained by the exhaustion of the lipidic reserves and/or a decrease of serum proteines particularly albumin, and consequently of transport in the blood of the fatty acids.

Adolescent↗