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Biomedical subjects

M Richard

Publications and source records attributed to M Richard.

At least 163 records · Page 9Linked to original sources
PubMed1978

[Spontaneous pneumomediastinum in adults. 10 cases (author's transl)].

Since it is relatively rare, spontaneous pneumomediastinum is often little known to clinicians. Making the diagnosis, however, presents no problem if the three essential signs are present, that is to say: -subcutaneous emphysema of the base of the neck (7 cases), -Hamman's sign, (6 cases), -a paramediastinal air shadow on chest roentgenograms, (8 cases). The condition is brought about by rupture of perivascular alveoli resulting in the migration of air along the pulmonary vessels. The principal advantage of making the diagnosis is that it enables one to eliminate other pain-causing thoracic syndromes, especially myocardial infarction, pulmonary embolus and acute pericarditis. The clinical course is usually benign necessitating no treatment.

Adolescent↗
PubMed1976

[Stimulation of pituitary gonadotropin secretion after castration in rainbow trout: variation of the response during the reproductive cycle].

Bilateral castration of male rainbow Trout resulted in increased levels of circulating gonadotropin, as measured by radioimmunoassay, but the response varied depending on the season. In early May the increase was 12 ng/ml after 30 days, when compared to the intact control but later in the month at the time when a peak of gonadotropin level is observed in normal fish, the increase was 25 ng/ml after 13 days. At the beginning of August, when spermatogenesis commences, the increase was 9 ng/ml after 12 days. In September, when spermatogenesis is ending, an increase of 20 ng/ml was found after 7 days, but only 50% of the animals responded. In December, during spermiation, an increase of 90 ng/ml was found after 7 days.

Animals↗
PubMed1976

[Glycosyltranferases. Biological and pathological importance].

Catalysing the transfer of oses and ose derivatives on various accepters, glucosyltransferases are of increasing importance in biology and pathology. Their sub-cellular localisation is now known together with the physico-chemical parameters of their activity and the importance of polyprenic intermediates. The first phenomenological studies concerning them are in favour of a mechanism of Bi-Bi type. For example, they may play a role in mucoviscidosis, virus diseases, vaccination and arthrosis.

Animals↗
PubMed1975

[Study of the concentration of glycosaminoglycans in cartilage from normal and osteoarthritic femoral head].

The biochemical composition of cartilage was studied in relation to the site of the sample and the age on 20 normal femoral heads and in relation to the histological appearance of the tissues on 34 arthrosic femoral heads. The collagen and glycosaminoglycan content of normal cartilage is identical in the four poles of the femoral head but becomes reduced with age. The chondroitin sulphate content falls slightly but slowly during ageing. In arthrosis, the glycosaminogylcan content is reduced when the cartilage is eroded and remains roughly normal when the cartilage is macroscopically normal or osteophytic. The cartilage of the osteophyte differs, however, radically from normal articular cartilage by a very high water content and by the presence of glycosaminoglycans which are mainly dialysiable. Similar modifications, that are less marked, occur in the macroscopically normal cartilage of the arthrosic femoral head and suggest the role of a disorder of glycosaminoglycan synthesis in the etiology of certain cases of arthrosis.

Age Factors↗
PubMed1975

[Phentolamine in treatment of acute left ventricular insufficiancies].

Phentolamine (Regitine) at the dose of 0.3 mg/mn behaves as an arterial and, above all venous, vasodilatator agent, resulting in a marked and early lowering of the pulmonary pressures in acute oedema of the lung and in cardiac asthma. It was used alone in 47 attacks of acute severe left ventricular failure with very favourable results in 43 cases, as proved by the rapid improvement of the haemodynamic status and of the aicd-base balance. Under strict observation, tolerance has been excellent. This therapeutic method seems of great interest in the cases of acute pulmonary oedema with a maintained blood pressure level, and in the forms with severe arterial hypertension which might tolerate larger doses.

Acid-Base Equilibrium↗