Interferon-induced translational regulation.
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Cell-Free System↗
Biomedical subjects
M Revel
Publications and source records attributed to M Revel.
Specific phosphorylation in vitro of a protein associated with ribosomes of interferon-treated mouse L cells.
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Interferons↗
Translational discrimination of 'capped' and 'non-capped' mRNAS: inhibition of a series of chemical analogs of m7GpppX.
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Cell-Free System↗
Antibodies to a cell-surface component coded by human chromosome 21 inhibit action of interferon.
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Alleles↗
Control of messenger RNA translation by minor species of leucyl-transfer RNA in extracts from interferon-treated L cells.
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Anticodon↗
Studies on the lactose operon. The control of DNA-directed in vitro protein synthesis by interference factor i-alpha.
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Acetyltransferases↗
The cell-free translation of SV40 messenger RNA.
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Cell Line↗
Blocks in elongation and initiation of protein synthesis induced by interferon treatment in mouse L cells.
Synthesis of polypeptide chains coded by exogenous messenger RNAs is inhibited in cell-free extracts from interferon-treated mouse L cells, due to a "deficiency" in some specific tRNA species. A detailed analysis shows that polypeptide chain elongation is blocked and incomplete chains are formed. After a few minutes, however, initiation of new polypeptide chains is also blocked. Messenger RNA still binds to ribosomes but initiator Met-tRNA(FMET) binding is inhibited. The block in initiation appears to be secondary to the block in elongation.
Animals↗
Proceedings: Discrimination messenger RNA by a mammalian translation initiation factor.
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Animals↗
Proceedings: Inhibition of the production of leukemia virus by interferon.
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Animals↗
Proceedings: Mechanism of the interferon-induced block of mRNA translation in mouse L cells and its reversal by tRNA.
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Animals↗
Proceedings: Purification and translation of mRNA coding for SV40 proteins.
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Animals↗
In vitro translation of polyadenylic acid-free rabbit globin messenger RNA.
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Adenosine Diphosphate↗
Mechanism of the interferon-induced block of mRNA translation in mouse L cells: reversal of the block by transfer RNA.
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Animals↗
mRNA specific initiation factors in the control of protein synthesis.
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Animals↗
Effects of interferon on hemoglobin synthesis and leukemia virus production in Friend cells.
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Animals↗
Selection of ribosome binding sites on mRNA in Escherichia coli by cistron-specific IF3 subfractions, and interference factors.
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Aminoacylation↗
Purification and properties of interference factor I: a cistron-specific translation control factor and a subunit of phage RNA replicase.
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Carbon Radioisotopes↗