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Biomedical subjects

M Reingold

Publications and source records attributed to M Reingold.

4 recordsLinked to original sources
PubMed1998

Isolation of a herpes simplex virus type 1-like agent from the brain of a mountain agile gibbon (Hylobates agilis agilis) with encephalitis.

A captive-born 2-yr-old male mountain agile gibbon (Hylobates agilis agilis) that died of encephalitis harbored a herpes simplex virus type 1 (HSV1)-like agent in the brain. A complete necropsy revealed intensive meningeal congestion with nonsuppurative encephalitis. The virus was recovered from frozen brain tissue in Vero cells. The isolate was very similar but not identical to human HSV1. Both western blot assay and virus neutralization tests were done with sera from 15 gibbons. Antibodies against HSV1 and herpes simplex virus type 2 (HSV2) were detected in four healthy gibbons, which included four species in three subgenera.

Animals↗
PubMed1982

Early presentation of carcinoma of the small bowel in Crohn's disease ("Crohn's carcinoma"). Case reports and review of the literature.

We report here 3 cases of adenocarcinoma of the small bowel complicating Crohn's disease ("Crohn's carcinoma"). In 2 cases, the adenocarcinoma was discovered in the first attack of enteritis. In only one other case in the literature, a similar presentation was described. A review of 59 reported cases of adenocarcinoma of small bowel in Crohn's disease, together with these 3 cases reveals that: (a) the cancer develops at a younger age than in carcinoma de novo; (b) there is no difference in incidence of carcinoma in the first, second, and third decades after the onset of symptoms of Crohn's disease; (c) in 73% of cases, the neoplasm rose in the ileum; (d) in all but 1 case it developed in inflamed segments of bowel; (e) in 31% of cases the cancer developed in a bypassed segment of bowel. This analysis clearly demonstrates that "Crohn's carcinoma" is a complication in Crohn's disease and not a chance coexistence of two diseases in the same patient.

Adenocarcinoma↗