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Biomedical subjects

M Reid

Publications and source records attributed to M Reid.

At least 181 records · Page 10Linked to original sources
PubMed1983

Inspection of the Bayley Mental Scale test materials for potential hazards of choking, aspiration, and ingestion when used outside of test situation.

The test materials of the Bayley Scales of Infant Development were inspected for potential choking, aspiration, and ingestion hazards by unsupervised children under 36 mo. of age. When the small-parts test cylinder, defined by the Federal Code of Regulations, was used for the inspection, four pieces of test materials were judged too small: the doll with detached head, sugar pellets, the rabbit, and yellow cubes.

Airway Obstruction↗
PubMed1981

Does anti-Jra cause hemolytic disease of the newborn?

A Jr(a-) Japanese female developed anti-Jra during her first pregnancy. Both father and infant red cells were Jr(+), and anti-Jra was eluted from the infant's red cells. The antibody was determined to be IgG1. Hemolysis could not be definitively established from the clinical data. The pitfall of using the presence of jaundice as the sole evidence for hemolysis is emphasized. We conclude that the present case, and other previously reported cases, do not unequivocally establish that anti-Jra significant hemolytic disease of the newborn (HDN). Amniocentesis probably should not be performed during the pregnancy of mothers sensitized to Jra antigen. Jra HDN is probably a mild disease, like ABO HDN.

Adult↗
PubMed1980

A glucose-dependent panhemagglutinin.

An agglutinin was identified in the serum of a non-transfused primiparous patient that reacted with all commercial red blood cells regardless of their antigenic makeup. The autologous control was negative. The agglutinin was directed against human red blood cells that had been incubated in media containing glucose and washed prior to testing. Red blood cells incubated in 2% glucose solution became agglutinable after 6 days of 4 degrees C or after 2 h at 37 degrees C. These red blood cells gradually became non-reactive when washed and incubated in saline at 37 or 4 degrees C. At 22 degrees C the titer of the agglutinin was 128 (score 64) in LISS and 64 (score 56) in saline. The agglutinin was denatured by 2-mercaptoethanol, but remained active after 30 min of heating at 56 degrees C. Among various mono- and disaccharides tested, glucose was the only sugar that selectively inhibited the reaction. The presence of such an agglutinin may cause confusion in a transfusion service laboratory by mimicking an antibody directed against a high incidence antigen.

Adult↗
PubMed1980

Individualized patient assessment in the treatment of epilepsy with sodium valproate.

This study records a comprehensive clinical protocol developed to assess seizure control and unwanted effects in 19 patients treated with sodium valproate (VPA). The assessment is based on six parameters individually ranked: seizure frequency, seizure duration, EEG comparisons, intellectual and cognitive function tests, sociological profile, and unwanted effects. Each parameter was ranked from one to five, and the mean was used to assess the overall patient state. Using this technique, this study assesses the therapeutic efficacy of VPA and the benefits of individualization of therapy as predicted by the use of pharmacokinetic parameters in a controlled trial.

Adolescent↗