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Biomedical subjects

M Ramos

Publications and source records attributed to M Ramos.

215 records · Page 12Linked to original sources
PubMedDate not supplied

[Agenesis of the right branch of the pulmonary artery, diagnosis by lung scan].

The white thrombus is formed due to the platelet adhesiveness to the vascular wall, and to their agglutination mediated by the liberation of ADP, the adenosine inactivation and the deposit of calcium and accelerating factors of coagulation as well. The red thrombus is formed by the thromboplastic activity, combined with the action of several coagulation factors, fibrin, erythrocytes and leucocytes. For the above mentioned facts, we may try to avoid the white thrombus formation by means of antiadhesive platelets drug, and the red thrombus production with the use of anticoagulants. If the thrombus is already formed, the drugs of choice are the fibrinolytics, to intend the dissolution of the clot. In the present paper, the mean characteristics as well as the actual concepts on the use of these three groups of drugs, are described.

Adult↗
PubMedDate not supplied

[Primary neuroendocrine carcinoma of the pavilion of the ear].

We present a case of primary neuroendocrine carcinoma (Merkel cell carcinoma) of the external ear and its treatment. This paper also deals with histogenesis, pathology, clinical findings, diagnosis and treatment of this tumor.

Antineoplastic Combined Chemotherapy Protocols↗
PubMedDate not supplied

The impact of service delivery frequency on family planning program output and efficiency.

Operations research is the study of factors that can be controlled by program administrators. Among such factors is the frequency of performing program activities. The present experiment, conducted in Lima, Peru during 1985-86, tested the impact of holding family planning post sessions once per month, twice per month, and weekly. Frequency was shown to have a major impact on program outputs, costs, and cost-effectiveness. Depending on the indicator, sessions held twice per month produced between 1.5 and 2.1 times the output of those conducted once per month. Weekly sessions produced between 1.3 and 1.6 times the output of those held twice per month. At an output level of nearly 11,200 visits per year, twice-per-month sessions were estimated to be 7-38 percent more cost-effective, depending on the indicator, than once-per-month sessions, and 6-28 percent more cost-effective than weekly sessions.

Community Health Services↗
PubMedDate not supplied

Spontaneous lymphokine activated killer (LAK) activity in bronchoalveolar lavage cells from patients with bronchogenic carcinoma.

Bronchoalveolar lavage cells (BAC) are considered to be representative of cells that are in the interstitium and in patients with lung cancer, may represent, in part, cells that infiltrate cancerous tissue. We used bronchoalveolar lavage (BAL) specimens to test the hypothesis that cells within this region might be regulated locally by factors and show activities that are dependent on these growth and activation mediators. We showed previously that Natural Killer (NK) activity and IL2 titers were proportional. As compared to normal subjects, patients with all stages of bronchogenic carcinoma consistently had very high levels of IL2 in their bronchoalveolar lavage (BAL) fluid and this titer correlated with an increase in NK activity in the BAC both in absolute level and in relative level to the blood. Now, we report results that show that spontaneous lymphokine activated killer (LAK) activity also can be measured in most patients, but not all patients, that express IL2 titers. These findings support the hypotheses that different types of nonspecific cytotoxic cells are present and active in cancerous lung specimens secondary to the secretion of lymphokines from activated T lymphocytes in that region and that LAK activity is a physiological phenomenon that may be expressed in regional rather than systemic areas of the body.

Bronchoalveolar Lavage Fluid↗
PubMedDate not supplied

Phenol lumbar sympathectomy in severe arterial disease of the lower limbs: a hemodynamic study.

The indications, results and evaluation methods of lumbar sympathectomy are very controversial. The authors present their experience and results with phenol lumbar sympathectomy (PLS). PLS (Reid's technique) was carried out in 25 patients with severe peripheral arterial disease. Sympathetic tone abolition was achieved in 72% of the patients, with a beneficial clinical effect in 60%. In this group, the following measurements were made, before sympathectomy, and 24 hours, one week and one month after it: Doppler ankle-pressure, ankle-arm pressure index and calf and foot arterial flow measured with an impedance plethysmograph (IPG), at rest and after controlled exercise. The IPG-measured arterial flow in the resting foot was the only parameter to show a significant increase following PLS (p less than 0.05). Although the IPG calf flow, ankle-pressure and ankle-arm index showed increases, these were not significant. Lumbar sympathectomy by phenol injection is as effective as by surgery. Its beneficial effect is believed to be due to an increase in the resting flow in the foot.

Adult↗
PubMedDate not supplied

Comparison of the Petrifilm dry rehydratable film and conventional culture methods for enumeration of yeasts and molds in foods: collaborative study.

A collaborative study was performed involving 18 laboratories and 6 food types to compare 3M Petrifilm yeast and mold count plates with the method described in the U.S. Food and Drug Administration's Bacteriological Analytical Manual. Four species of mold and 2 species of yeast were used to inoculate the following foods: hot dogs, corn meal, ketchup, orange juice, yogurt, and cake mix. Each collaborator received 15 samples of each food type: 5 low-level inoculations, 5 high-level inoculations, and 5 uninoculated samples. There was no significant difference between the means of the 2 methods for any product or inoculation level. The Petrifilm yeast and mold count plate method for enumeration of yeasts and molds in foods has been adopted first action by AOAC INTERNATIONAL.

Aspergillus↗
PubMedDate not supplied

Antiphospholipid antibodies in primary Sjögren's syndrome: prevalence and clinical significance in a series of 80 patients.

OBJECTIVE: To determine the prevalence and clinical significance of antiphospholipid antibodies (aPL) in a cohort of patients with primary Sjögren's syndrome (SS). METHODS: Eighty patients with primary SS were studied prospectively. The prevalence of aPL and characteristics of the clinical and laboratory features of these patients were compared with those of the following groups of patients: (i) 50 patients with SS associated with systemic lupus erythematosus (SLE); (ii) 100 patients with SLE without SS; and (iii) 100 healthy blood donors from the blood bank of our hospital. RESULTS: Only 11 (14%) patients with primary SS were found to have aPL (anticardiolipin antibodies or lupus anticoagulant, or both) in their sera, but anti beta 2-glycoprotein I antibodies were not detected in any patient. In contrast, aPL were detected in 12 (24%) patients with SS secondary to SLE and in 21 (21%) patients with SLE without SS. None of the healthy controls presented aPL in their sera. Patients with primary SS presented a lower prevalence of thrombocytopenia (p < 0.05) and livedo reticularis (p < 0.01) compared with the other two groups of patients. No patient with primary SS was diagnosed as having an antiphospholipid syndrome (APS), while 4 (8%) patients with secondary SS and 9 (9%) with SLE without SS were found to have APS (p < 0.05). CONCLUSION: In patients with primary SS, aPL are present in a lower percentage than in patients with SS secondary to SLE or in patients with SLE without SS. The presence of aPL in these primary SS patients is not associated with the clinical events of APS.

Adult↗
PubMedDate not supplied

Antiphospholipid syndrome without antiphospholipid antibodies at the time of the thrombotic event: transient 'seronegative' antiphospholipid syndrome?

The antiphospholipid syndrome (APS) is characterized by the presence of venous and arterial thrombosis, recurrent fetal losses and thrombocytopenia, associated with the presence of antiphospholipid antibodies (aPL). This syndrome may be "primary" or may be associated with other diseases, mainly systemic lupus erythematosus (SLE). However, some patients present the clinical picture of this syndrome but without evidence of aPL in their serum. The term "seronegative" APS has been proposed to categorize these patients. Here with we present two patients with seronegativity for aPL at the time of a thrombotic event, but in whom these antibodies were detected 2 and 7 months later.

Adult↗