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Biomedical subjects

M Rădulescu

Publications and source records attributed to M Rădulescu.

34 records · Page 2Linked to original sources
PubMedDate not supplied

[Difficulties of diagnosis and surgical treatment in gallbladder cancer].

After a review of the etiopathogenic data, as well as of anatomo-pathologic aspects of the cancers of the gall-bladder the authors stress the difficulties of diagnosis encountered in the pre-surgery stage, and during the surgical intervention. In view of an early detection of neoplastic lesions the authors suggest extemporaneous histo-pathogenic examination of the lithiasic gall-bladder. They prefer the transparietal-hepatic cholangiography, and the intraoperative transhepatic cholangiography for an exact assessment of the convergence point of hepatic canals, with a view to perform peripheral hepato-digestive derivations. In the 90 cases of cancers of the gall-bladder, of which 75 (87%) were associated (with 4 deaths), cholecystectomy with atypical hepatectomy in one case, cholecystectomy with choledochs drainage in 4 cases (with one death), cholecystectomy with choledochal-duodenostomy in 2 cases, cholecystectomy in 18 cases (with 3 deaths), cholecysto-gastrostomy in 2 cases, hepato-gastronstomy in 13 cases (with 3 deaths), hepato-cholangio-jejunostomy in 2 cases, and exploratory laparotomy in 35 cases. In view of prophylaxis of gall-bladder cancer the authors suggest that cholecystic lithiasis in patients over the age of 40 years should be treated by cholecystectomy.

Adenocarcinoma↗
PubMedDate not supplied

[Suppurated acute obstructive cholangitis. Anatomoclinical and therapeutic aspects].

A total of 134 cases are discussed, with suppurated acute obstructive angiocholitis, that underwent surgical treatment over a period of 10 years, representing 12,8% of the total number of organic obstructions of the hepato-choledocus. From the standpoint of the etiopathogenic mechanisms the angiocholitis was determined by biliary lithiasis in 59 cases, by sclerosis of the Oddi sphincter in 5 cases, by postoperative cicatriceal stenosis of the main biliary pathway in 2 cases, by hepatic hydatitosis in 16 cases, by Vater ampuloma in 10 cases by cancers of the main biliary pathway in 40 cases and by the congenital cyst of the choledocus in one case. The high frequency was noted, of the severe forms of ictero-uremigenic angiocholitis (representing 68 cases, or 50,7% of the total, with a death rate of 34%). Medico-surgical treatment should be performed as early as possible, and it must be intensive, complex, and adapted to the anatomo-clinical forms. The authors performed evacuation choledocotomy with external draining in 22 cases (3 deaths), and choledoco-duodenal anastomosis in 46 cases (10 deaths), choledoco-jejunostomia in 3 cases, Oddi sphincterotomia in 12 cases (2 deaths) ampulectomia in 5 cases (2 deaths). Peripheral bilio-hepatodigestive anastomoses were performed in 40 cases with 5 deaths.

Adolescent↗
PubMedDate not supplied

[Lithiasic cholecysto-choledochal fistulas. Peculiarities of diagnosis and surgical treatment].

On the basis of a study of 16 cases the authors discuss the etiopathogenic, anatomo-pathologic and therapeutic aspects of biliobiliary fistulae. The age of the patients ranged between 27 and 75 years and all had biliary lithiasis for a long time. The authors stress the difficulties of the pre- and intraoperatory diagnosis, as well as the surgical methods of treatment. In relation to the anatomo-clinical forms the authors have performed the following types of intervention: cholecystectomy with evacuatory choledocotomy and Kehr drainage (9 cases) - with 2 deaths, and a failure, evacuatory choledocotomy with external biliary drainage in one case, choledocoduodenostomy (3 cases) - with one death, Oddi sphincteroplasty (2 cases), and hepato-jejunostomy in one case.

Adult↗