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Biomedical subjects

M R Sarkar

Publications and source records attributed to M R Sarkar.

22 records · Page 2Linked to original sources

Induction of monocyte chemotaxis in devascularized rabbit bone.

Temporary impairment of blood supply has been suggested to cause bone remodeling. The degradation of cells and matrix and the attraction of resorbing cells were examined in this study. Bone specimens of rabbits were stored in vitro for 2-20 days. At the end of this aging process the probes were tested for their chemotactic activity toward autologous leukocytes in a diffusion chamber. Both supernatant from the aged bone specimens and ground bone particles exhibited significant chemotactic activity that was specifically attracting monocytes. It is suggested that soluble bone matrix proteins or degeneration products liberated during ischemic damage to cortical bone initiate the resorptive process.

Animals↗

[Obturator dislocation of the hip joint].

Luxatio obturatoria may occur in the case of a trauma affecting the hip joint when the latter is in a position of flexion, abduction and external rotation. The femoral head dislocates anteriorly and caudally towards the foramen obturatum. A recent case will be presented with a discussion of the general aspects of this injury, with special emphasis on concomitant injuries and their significance of the long-term prognosis.

Femur Head↗

[Luxatio humeri erecta. A rare form of inferior shoulder dislocation].

In patients with erect dislocation of the shoulder, the arm is typically locked in an upright position. This rare variant of subglenoid luxation always causes damage to the ligamentous structures of the joint and sometimes additional complications arise from neurovascular lesions. Two recent cases are reported here. The mechanism of injury, therapeutic measures and prognosis are discussed.

Accidental Falls↗

[Fractures of the upper extremity in the elderly].

PROBLEM: The primary goal in treating fractures in elderly persons is safe and rapid restoration of their functional capabilities to secure independence in everyday activities. The intention of this paper is to present an overview of treatment principles useful in this age group. METHODS: We analysed a series of 404 patients above the age of 70 years who underwent surgery for fractures of the arm between 1981 and 1997. RESULTS: Diaphyseal fractures are less frequent in this age group and their treatment does not differ significantly from principles established for younger patients. The majority of fractures of the proximal humerus and the distal radius can be treated by conservative means. Unstable fractures are frequent in the distal humerus and the olecranon requiring operative reduction and osteosynthesis. CONCLUSIONS: Preferred operative techniques in aged persons inflict minimal surgical trauma and have a low rate of complications and secondary interventions. In contrast, anatomical reconstruction has the highest priority in younger individuals.

Aged↗