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Biomedical subjects

M R Mickey

Publications and source records attributed to M R Mickey.

At least 127 records · Page 7Linked to original sources

Lymphocyte transformation induced by human granulocytes.

Contrary to previous reports, human granulocytes are capable of causing transformation of allogeneic lymphocytes. Pretreatment of granulocytes with mitomycin C results in nonstimulation, but untreated granulocytes are capable of stimulating lymphocytes. Nonstimulation with mitomycin C-treated granulocytes may result from the reduced viability of the cells. It is concluded that granulocytes possess alloantigens that stimulate lymphocytes in vitro.

Cell Count↗

Cystic fibrosis complicated by heart failure.

Survival studies were done on 36 children with cystic fibrosis and heart failure. Thirty percent did not survive the first four weeks, and the median survival for the group was between two and three months. By the end of the first year from the onset of failure, 74 percent had died and at 30 months, 87 percent had died.

Adolescent↗

Effect of water-soluble adjuvants on in vitro lymphocyte immunization.

Water-soluble adjuvants prepared from Mycobacteriim smegmatis and human mixed mycobacteria strains C, DT, and PN were found to increase lymphocyte response in one-way mixed-lymphocyte culture and in vitro immunization to cultured human tumor cells. Phytohemagglutinin-induced lymphocyte blastogenesis, however, was depressed by water-soluable adjuvants.

Adjuvants, Immunologic↗