Search PubMed⌕ Search

Biomedical subjects

M R Mickey

Publications and source records attributed to M R Mickey.

179 records · Page 10Linked to original sources
PubMedDate not supplied

Ninety-five percent probability of paternity with HLA, ABO and haptoglobins.

Using HLA tissue typing as the basic genetic test along with ABO and haptoglobin typing, it is generally possible either to exclude a putative father conclusively or, in nonexclusion cases, to assign a greater than 95% probability of paternity. In 22 of 53 nonexclusion cases, the putative father had a probability of paternity above 99% based on these genetic tests.

ABO Blood-Group System↗
PubMedDate not supplied

The effect of individual HLA antigens on graft survival rates in kidney transplant patients.

We have used information available in the UCLA International Transplant Registry to study the effect of HLA antigens on graft survival outcome. All results showed that of all antigens tested, the presence of DRl in the recipient was associated with the highest graft survival rate. There was a positive matching effect for most DR antigens that were either presumed homozygous or heterozygous in the recipient. A regression analysis not only confirmed the association of DR1 and low immune response, but also suggested a greater importance of the DR rather than A or B locus to graft survival rates. Recipients with DR1.5 had the highest survival rates when DR1 was compared with other DR antigens and the heterozygous combinations of the two groups. This suggests that presence of heterozygous DR antigens may have combined effects on graft survival.

Follow-Up Studies↗