Search PubMed⌕ Search

Biomedical subjects

M R Jain

Publications and source records attributed to M R Jain.

At least 37 records · Page 2Linked to original sources
PubMed1978

Ocular penetration of hydrocortisone and dexamethasone into the aqueous humour after subconjunctival injection.

The concentration of steroids in the aqueous humour was measured at various intervals after subconjunctival injection in a series of 130 patients of both sexes who came to cataract extraction. Both hydrocortisone acetate (0.5 ml of 2.5 per cent solution) and dexamethasone sodium phosphate (0.5 ml of 0.4 per cent solution) attained a peak concentration in the aqueous of 214.4 and 268.0 micrograms/ml respectively within 10 minutes. Dexamethasone was from 30 to 47 times more effective than hydrocortisone for up to 24 hrs, but the latter provided a reasonably high concentration for up to 7 days.

Aqueous Humor↗
PubMed1976

Rapid pneumatic and Mackey-Marg applanation tonometry to evaluate the postural effect on intraocular pressure.

A postural study was conducted in three separate groups of subjects. The first group comprised 20 women volunteers with an average age of 20-75 years. In this group, the study was conducted by the pneumatonograph only. Mean pressure recorded was 15-65 +/- 0-25 mmHg and there was an average rise of 1-4 mmHg in supine posture. Groups 2 and 3 comprised 151 non-glaucomatous and 108 glaucomatous eyes respectively in the age range of 30 to 85 years. In these two groups, the study was conducted using the PTG and the Mackay-Marg tonometer. Clinical evaluation of the Mackay-Marg with the PTG gave significant correlation, with mean Mackay-Marg readings being 1-13 mmHg higher. The intraocular pressure when changing from seated to the supine position increased on average by 2-71 and 4-04 mmHg, respectively in Groups 2 and 3 and by 2-51 and 3-72 mmHg by Vackay-Marg, suggesting a higher change in glaucomatous subjects. Pressure on resumption of sitting was found to be lower than the initial pressure. Postural change also showed some direct relationship with age in non-glaucomatous subjects.

Adolescent↗
PubMed1976

A clinical evaluation of the applanation pneumatonograph.

The applanation pneumatonograph combines pneumatic and electronic systems. It is used for measuring intraocular pressure, aqueous humour dynamics, and ocular pulsation. In the present study the PTG and the Goldmann tonometer have been used to measure the intraocular pressure in 40 normal and 40 glaucomatous eyes. It has been found that the results of the two instruments correlate well. The PTG readings have, generally, been found to be higher with a mean difference of 0-75 mmHg in the normal and 1-25 mmHg in the glaucomatous eye. The mean ocular pulse as determined in normal eyes was 3-25 +/-0-21 mmHg.

Aged↗