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Biomedical subjects

M R Escobar

Publications and source records attributed to M R Escobar.

At least 37 records · Page 2Linked to original sources
PubMed1975

Biphasic local reaction to a new insulin (U-100).

The phenomenon of localized insulin reaction is described and illustrated by the report of a case. The patient's unusual response consisted of an "early" and a "late" phase to single-peak and single-component insulins. No definite immunologic mechanism was established on the basis of immunologic studies or from histologic examination of skin biopsies.

Adult↗
PubMed1975

Transportation delay and the microbiological quality of clinical specimens.

An in-use study was done to determine the effect of transportation delay on the microflora of clinical specimens collected for microbiological analysis in a 1,000-bed university hospital. Portions of wound, respiratory, and urine specimens were planted for bacterial isolation on the wards immediately after collection. The remainder of each specimen was kept at room temperature without or without holding medium until it was picked up by messengers and taken to the bacteriology laboratory. The results of immediate planting on the ward were compared with those obtained by planting in the laboratory. Alterations in microflora were observed in all three types of specimens after averages of 2 to 4 hours of delay in planting.

Humans↗
PubMed1975

Lymphomatoid granulomatosis of the skin. A new clinocopathologic entity.

Lymphomatoid granulomatosis is a necrotizing arteritis primarily affecting the lungs but also found in the skin, kidneys, central nervous system, and other extra-pulmonary sites. Cutaneous involvement occurred in 45% of the cases described by Liebow in his original series. Light microscopy studies were performed. The IgA and IgG levels were slightly decreased and the IgE level was elevated. Cell-mediated immunity was impaired. No viruses were isolated or identified by immunofluorescence. A man had cutaneous lesions as the first sign of lymphomatoid granulomatosis.

Aged↗
PubMed1974

Pulmonary infection due to disruption of the pharyngeal bacterial flora by antibiotics in hamsters.

An animal model was used to determine the effect of oxacillin on the pharyngeal bacterial flora and the relationship of this flora to pneumonia. The pharyngeal bacterial flora of 68 healthy Golden Syrian hamsters was determined. A quantitative comparison between Streptococci and Escherichia, Proteus, Klebsiella and Enterobacter from 70 hamsters was made before and at 4, 24, 48 and 72 hours after oxacillin administration. Lung cultures were positive in 22 of 25 hamsters, yielding K pneumoniae type 1 most frequently. Lung histology from 25 hamsters revealed bronchopneumonia. Intestinal postmortem cultures of treated and untreated animals were similar. The importance of throat cultures in diagnosing pneumonia and the value of the hamster model to study the effect of other antibiotics on the temporary flora are demonstrated.

Animals↗
PubMed1971

Correlation of staphylococcal bacteriophage types to L-form colony production.

The ability of 258 strains of Staphylococcus aureus and 132 strains of S. epidermidis to produce L-form colonies in a standard environment was investigated. Production of these colonies by S. aureus was correlated with their phage type. Phage type 7 strains produced L-form colonies in larger numbers and more consistently than those of phage type 80/81. No L-form colonies were produced by the S. epidermidis strains tested.

Journal Article↗