Leucocyte migration inhibition by tumour-associated antigens in human bladder carcinoma.
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Biomedical subjects
Publications and source records attributed to M R Butler.
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The results of serial urodynamic studies in spinal cord injury are presented. A number of signs which may be useful in the prediction of patients who will eventually establish spontaneous and satisfactory voiding are described. (1) Some patients with cervical high/thoracic lesions show evidence of synchrony between the external sphincter and the detrusor muscle in the phase of spinal shock. Spontaneous and efficient voiding usually occurs in this group. (2) Some patients, especially those with mild-thoracic lesions show marked dyschrony between the external sphincter/detrusor muscle in the phase of spinal shock. Early outlet surgery is indicated in this group since spontaneous and efficient voiding rarely occurs. (3) A zone of high pressure can be detected in the posterior urethra in the phase of spinal shock often within the first week after injury.
The intravenous urograms of 894 patients with acute retention were assessed. The total number of lesions demonstrated was less than 1 per cent; consequently the value of routine intravenous urograms in patients with acute urinary retention is questioned.
Two groups of aphasics were administered an auditory comprehension task under conditions of 0-, 5-, and 10-sec. imposed delay of response. The auditory-visual group received auditory and visual cues; the auditory group received only auditory cues. Comprehension for the auditory-visual group was significantly better than for the auditory group. Increase in delay time significantly improved comprehension for the auditory-visual group but not for the auditory group.
Over a ten-year period, 129 patients with idiopathic pelviureteric obstruction were randomly selected for splinted or unsplinted pyeloplasties. Of these groups, the patients with splinted pyeloplasties had a lower incidence of postoperative complications. The long-term results were similar in both groups.
Relapse occurred in 53 cases out of 838 consecutive cases of genito-urinary tuberculosis, followed for periods of 11 months to 27 years. Initial and recurrent disease is classified, and the treatment given is described. Length of inactivity is estimated, and correlated with the type of therapy given. Sensitivity of the organisms to chemotherapy is stated. Conclusions suggest that a life-long follow-up, at yearly intervals, of patients with genito-urinary tuberculosis is justified, as recurrences are diagnosed early, destructive changes are than unlikely, further surgery may be avoided, and a repeat course of chemotherapy is usually curative.
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BACKGROUND: Management of traumatic rupture of the male membranous urethra remains controversial. Long-term morbidity can include urinary incontinence, urethral stricture and erectile dysfunction. AIMS: To review management and outcome of urethral rupture to improve treatment protocols. METHODS: A retrospective study of 47 patients presenting with traumatic urethral rupture over 25 years was performed. RESULTS: All patients underwent emergency suprapubic catheterisation, 32 patients had open surgical realignment at 1-2 weeks; 78% of whom developed strictures. Ten patients unsuitable for early repair underwent delayed transabdominal transpubic urethroplasty at three months: 40% of whom developed strictures. Five patients with partial rupture were managed by cystoscopy and urethral catheter. Erectile dysfunction correlated to initial injury rather than treatment. CONCLUSIONS: If the patient is stable and requires emergency laparotomy for other abdominal injuries, he should have immediate realignment of the urethra. Early realignment of the urethra at laparotomy at 1-2 weeks can be combined with orthopaedic fixation of pelvic fractures. Patients who remain unstable due to associated injuries should have delayed urethroplasty at three months.
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