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Biomedical subjects

M R Alexander

Publications and source records attributed to M R Alexander.

38 records · Page 3Linked to original sources

Use of androgens in chronic renal failure patients on maintenance hemodialysis.

The etiology of anemia associated with chronic renal failure, and the advantages and disadvantages of its treatment with androgenic agents, are reviewed. Clinical trials with the following types of androgenic agents are reviewed: 17-alpha-alkylated androgens, testosterone esters, and 19-nortestosterone derivatives. The studies indicate that androgens stimulate erythropoiesis in chronic renal failure patients. However, because of the risk of serious adverse effects, the use of these agents should probably be restricted to those patients who have or may become symptomatic.

Androgens↗

Utilization of electronic infusion devices in a university hospital.

Use of large-volume electronic infusion devices (EID) in an adult general hospital was compared with an established protocol to determine compliance. Data were collected during seven widely spaced inspections of the facility. Forty-six percent of 962 EID were observed to be employed inappropriately. Compliance was nearly identical for both pumps and controllers and for intensive care and non-intensive care areas. Four reasons for employing EID accounted for 48 percent of all inappropriate use. An estimated annual savings of +178,000 to +460,000 might be realized through strict protocol compliance.

Costs and Cost Analysis↗