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Biomedical subjects

M Puccini

Publications and source records attributed to M Puccini.

20 records · Page 2Linked to original sources

[Ectopic parathyroid glands in primary hyperparathyroidism].

The incidence of the ectopic parathyroid glands seems to be different between normal subjects and patients affected by primary hyperparathyroidism. We reviewed a serie of patients operated on for primary hyperparathyroidism in our Institute between 1985 and 1991, and the reports from literature about this mean; the frequence of ectopies is = 31% (10.3% in the upper- anterior mediastinum). These findings are similar to those reported in the literature. The higher incidence of ectopies in the hyperparathyroid group respect to the normal one and the surgical problems that it could cause represent a reinforcement of the concept that parathyroid surgery should be done only by an experienced, technically and theoretically prepared surgeon, and may justify the use of non invasive, non expensive imaging techniques at the first cervical exploration for suspected hyperparathyroidism, in order to ameliorate the results and in particular to solve suddenly some dramatical cases due to major parathyroid ectopies.

Adolescent↗

Thyroid surgery in patients aged over 80 years.

In the past 5 years (1987-1991), we admitted for thyroid surgery 12 patients older than 80 years. Indications for surgery were represented by goiter causing tracheal compression and severe dyspnoea in 6 cases, and by preoperative cytological report of malignancy in the other 6 cases. The dyspnoea represented an absolute surgical indication. All patients but one were treated by cervicotomy; in one case we performed a median sternotomy. Frozen section was performed in all patients with cytological report of malignancy. Histology detected 3 differentiated cancers, 2 anaplastic cancers, and one follicular adenoma. The patients with benign disease were treated by 4 subtotal thyroidectomies and 3 total lobectomies. Three out of 5 affected by malignant lesions were submitted to a total thyroidectomy (differentiated carcinomas) and 2 to palliative thyroidectomy (anaplastic carcinoma). In this series there were neither intraoperative mortality nor major surgical complications. All the patients with dyspnoea were cured by surgery. All the patients affected by differentiated cancer were alive and well 8, 13 and 18 months after surgery. The mean survival of patients with anaplastic cancer was 12 months.

Adenoma↗