PURPOSE: The reactivity and patency of balloon-expandable Strecker stents were determined in the superior vena cava (SVC) and inferior vena cava (IVC) of rabbits. MATERIALS AND METHODS: One stent was placed in each of 24 rabbits; 15 were placed in the SVC and nine in the IVC. The duration of stent placement varied between 3 days and 15 months. After the animals were killed, the segments in which the stent was placed were sectioned and analyzed under light microscopy for quantification of neointimal hyperplasia with metal struts in situ. RESULTS: Twenty-three stents remained patent throughout. Two SVC stents thrombosed at 1 week; one of these recanalized spontaneously after 4 weeks. Self-limiting neointimal hyperplasia reached a maximum thickness at 1 month and receded over 3-6 months. In five rabbits with long-term SVC stents, there was a radial shift of the stent to the perivascular layer of fat. Despite this shift, these stents remain patent. CONCLUSION: Strecker stents are well adapted to the venous system in terms of both patency and histocompatibility.

Animals↗

PubMedDate not supplied

[Multiple primary malignant melanomas. A report of five cases (author's transl)].

The authors present 5 cases of primary malignant melanomas occurring simuatlneously or successively, diagnosed at Institut Gustave Roussy over a period of 10 years. This work emphasizes the need for searching possible changes of nevi in melanoma patients.

Adult↗

PubMedDate not supplied

Fine needle aspiration of the liver and pancreas with ultrasound guidance.

The experience of the Institut Gustave-Roussy in the diagnosis of hepatic and pancreatic lesions by fine needle aspiration (FNA) is reported. Totals of 116 consecutive percutaneous ultrasound-guided FNAs of the liver and 27 of the pancreas were performed without complication in patients with ultrasonically suspected neoplastic lesions. In 12 cases, the material was not suitable for diagnosis. In the liver, 97 cases were correctly diagnosed and confirmed by follow-up. Immunohistologic studies were helpful in distinguishing primary liver tumors from other malignancies. One false-positive result was reported. In the pancreas, malignancy was detected in 17 cases. Cytology alone provided the correct tumor diagnosis in 15 cases: 10 primary carcinomas, 2 endocrine tumors and 3 metastases. The sensitivities of FNA in this study were 87.6% for the liver and 85% for the pancreas, similar to those reported in other series.

Biopsy, Needle↗

PubMedDate not supplied

[Prognostic study and remote results of the treatment of a series of 160 malignant cutaneous melanoma of cervicofacial localization].

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Adolescent↗

PubMedDate not supplied

[Role of electrocoagulation in treatment of cancers of the rectum].

The authors describe the technics of a wide local electrocoagulation which was used in the treatment of 42 malignant tumors of the rectum: 27 adenocarcinomas and 15 malignant villous tumors. This not disabling technic, avoiding colostomy, is generally harmless even in old and poor risk patients. The mortality rate was 7 p. 100 in the adenocarcinomas series, nul in the malignant villous tumor series. The five year survival rate was 66 p. 100 in the first series and 80 p. 100 in the second. One third of the patients bearing adenocarcinomas developed recurrences, among which some were treated either by large surgery, iterative electrocoagulation, or radiotherapy after colostomy. The indications depend on the size and the site of the tumor. Electrocoagulation is found possible only for T1 or T2 tumors of the posterior and lateral walls of the rectum, provided that they are located at less than 10 cm from anus and above the sphincter.

Adenocarcinoma↗