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Biomedical subjects

M Poussa

Publications and source records attributed to M Poussa.

64 records · Page 4Linked to original sources

The effect of the thickness of the cortical bone on bone formation by osteoperiosteal grafts. A comparative study employing routine histological stains and triple fluorochrome labelling.

The bone-forming capacity of free periosteum was compared with that of 100 micrometers thick osteoperiosteum and periosteum with full thickness cortex taken from the tibia of 6-week-old rabbits. Altogether 78 rabbits were operated on. The results revealed that the osteogenic capacity of free periosteum and 100 micrometers thick osteoperiosteum was about the same, and that osteoperiosteum with full thickness cortex was inferior in this regard.

Animals↗

Vascularization of free periosteal and 100 micron thick osteoperiosteal grafts in muscle tissue environment.

The vascularization of free periosteal and 100 micron thick osteoperiosteal grafts was studied in growing rabbits. Sixteen rabbits with 32 periosteal and 32 osteoperiosteal grafts were operated upon and microangiographed 1-21 days postoperatively. The vascularization of free periosteal grafts started 1 day postoperatively and that of osteoperiosteal grafts 3 days postoperaitvely. The first capillaries seemed to enter through the cambium layer in periosteal grafts and through the cortex in osteoperiosteal grafts.

Angiography↗

The osteogenic capacity of free periosteal and osteoperiosteal grafts. A comparative study in growing rabbits.

The behaviour of free periosteal and 200 micron thick osteoperiosteal grafts was studied histologically in 40 six-week-old rabbits. The grafts were taken from the tibia and fixed on either side of the same lumbar vertebra between the spinous and mamillary processes. The free stripped periosteum had better osteogenic activity than the 200 micron thick osteoperiosteum. The new bone was formed by the osteogenic cells of the cambium layer in both types of graft.

Age Factors↗

Intraosseous lipoma of the calcaneus. Report of a case and a short review of the literature.

One case of an intraosseous lipoma of the calcaneus bone is presented together with a short review of the literature. Only 20 cases of tumors in the extremities have so far been published. The typical X-ray picture shows a cystic, sharply demarcated cavity, which macroscopically at operation is filled with yellowish, adipose tissue. In the present case and one previously published a central sclerotic mass was observed. The histological picture is typical, with mature adipose tissue mixed with a few degenerated bone trabeculae.

Adult↗

Intertrochanteric varus osteotomy in Legg-Calvé-Perthes disease: a report of 112 hips.

The results of 112 intertrochanteric femoral varus osteotomies performed on 102 children with Legg-Calvé-Perthes disease were analyzed. The result worsened with the increasing age of the patient at operation. It was seldom good when the patients age was greater than or equal to 9 years. Catterall grouping and the concept of head at risk were of prognostic significance in patients operated on before 9 years of age and before the disease had reached the healing phase. No correlation was observed between the result and the femoral neck-shaft angle measured preoperatively and after consolidation of the osteotomy.

Age Factors↗

Spondylolisthesis in children under 12 years of age: long-term results of 56 patients treated conservatively or operatively.

Thirty-six girls and 20 boys who were diagnosed with spondylolisthesis of L5 when aged less than 12 years (10 months to 11 years) were reexamined clinically and radiologically at skeletal maturity, 5-30 years (average 14.5 years) later. Thirty-two children were treated operatively: 20 patients by posterior, 10 by posterolateral, and one child by anterior fusion. One patient had laminectomy only. None of the patients treated conservatively had later operative treatment. Clinical symptoms leading to operative or conservative treatment, results of treatment, and radiologic changes are reported. Girls had more severe displacement, earlier worsening of deformity, and more clinical symptoms than boys. The role of growth spurt in progression of the slip is discussed. The importance of regular clinical checks of young children with spondylolisthesis is stressed.

Child↗

Biological factors and predictability of bracing in adolescent idiopathic scoliosis.

Biological factors that could have a predictive value in treating idiopathic scoliosis by brace were studied in 107 patients (102 girls and 5 boys). The mean age of the patients was 14 years 6 months, and the mean Cobb angle of the curves was 36 degrees at start of treatment. The Boston brace was used for an average of 1 year 6 months, and mean follow-up time after weaning was 3 years. Scoliosis with an apex of Th 10-12 proved to be the most favorable for the final result, with a mean correction of 2 degrees. All other curves remained unchanged. Patients who had a period of rapid growth just before or during treatment had a better final result than the others. The final result was also better when treatment was started before menarche.

Adolescent↗

Cervical spine in diastrophic dysplasia: an MRI analysis.

In this cross-sectional study, we evaluated the cervical spine in patients with diastrophic dysplasia (DD) by using magnetic resonance imaging (MRI). From 90 (57 female, 33 male) patients of different ages (0.3-56.0 years), T1- and T2-weighted images were obtained. The craniocervical junction and status of the medulla were examined, and the transverse areas of dural tube and medulla were measured. Alignment of the cervical spine, vertebral abnormalities, and disc changes also were evaluated. The cervical spinal canal was moderately narrowed, particularly in adults. The transverse areas of the medulla and especially of the dural tube were smaller compared with a normal population (p < 0.0001). There was no stenosis of the foramen magnum in patients with DD, but the spinal canal was narrowed. Degenerative changes were common. In all age groups, intervertebral discs were dark and disc heights were narrowed. Three (3%) patients (two children, one adult) had cervical kyphosis. Compression of the medulla was noted in association with severe cervical kyphosis in one child and one adult. Typical findings of the cervical spine in DD were exceptionally wide foramen magnum, narrowed spinal canal and early degenerative changes, and in older age groups, especially midcervically narrowed spinal canal. Severe cervical kyphosis caused medullar compression. The intervertebral discs developed abnormally. Abnormal disc structure may be one etiologic factor in the development of cervical kyphosis. Early and rapid progression of the degenerative changes is a normal finding in patients with DD, regardless of their age, and this also explains the stiffness of the cervical spine in clinical examination.

Adolescent↗

Metaphyseal distraction for lower limb lengthening and correction of axial deformities.

Metaphyseal distraction with the Orthofix apparatus was performed on 10 patients (five femora and five tibiae). A retrospective review is presented. The follow-up time was 10-38 months. A satisfactory correction of leg length and axial deformity was achieved in all cases. There was no need for plating or bone grafting. All patients showed solid bony fusion at follow-up. Pin tract infections in seven patients resolved under antibiotic treatment. Problems of pin loosening and mechanical weakness of the distraction device are discussed.

Adolescent↗

Intertrochanteric varus osteotomy in the treatment of Perthes' disease.

Seventy-eight hips with Perthes' disease (LCPD) were treated with an intertrochanteric varus osteotomy. The hips were preoperatively graded according to Catterall's classification. There were 7 Group II, 32 Group III, and 39 Group IV hips. Good results occurred in 5 of the Group II hips, 19 of the Group III hips, and 12 of the Group IV hips. The average age of the patients at the onset of symptoms was 6 years and 6 months, and the average age at the time of the osteotomy was 7 years and 8 months. This means that the average age of patients was high and that the operations were performed in a late state of the disease. A control group consisting of 52 hips was treated conservatively with a Thomas splint. In 11 hips classified as Catterall's Group IV, there were 8 poor results. The results indicate that with osteotomy the results improve in Group IV of Catterall's classification. There are, however, still about 30% poor results in the Group IV. A prolonged prevention of weight-bearing after osteotomy may be indicated in patients with unfavorable results.

Child↗