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Biomedical subjects

M Pollard

Publications and source records attributed to M Pollard.

At least 145 records · Page 8Linked to original sources
PubMed1972

Responses of lymphocytic choriomeningitis carrier mice to X-ray-induced lymphoma.

The data presented in this paper define the interrelationship between two endogenous diseases in the same host. The Haas strain of germfree mice with congenitally acquired persistent lymphocytic choriomeningitis (LCM) virus infection developed the X-ray-induced lymphatic leukemia independent of LCM viremia. The immunoproliferative LCM-related lesions appeared after age 7 months, and the radiogenic lymphatic leukemia appeared earlier or during the same age period. Both diseases evolved with distinctive lesions at the appropriate time, with no evidence of interference nor of synergism between the two syndromes. The Haas strain of mice showed an unusual sensitivity to X rays which was associated with depletion of blood components and coincident death. The sensitivity of the mice to X rays might be a characteristic of the Haas mouse or the result of an LCM virus-induced alteration in hematopoiesis.

Animals↗
PubMed1971

The germfree rat.

Explore the source record for details and available documents.

Adenocarcinoma↗
PubMed1970

Responses of the Peyer's Patches in Germ-Free Mice to Antigenic Stimulation.

Lymph nodes, spleens, and Peyer's patches of germ-free mice are relatively inactive. The tissues are small and contain rare, small, indistinct, germinal zones. When exposed to antigenic stimuli (Salmonella paratyphi A and lymphocytic choriomeningitis virus), the tissues become larger and germinal zones appear coincident with antibodies in the blood. The Peyer's patches were activated if antigen was absorbed from the intestinal lumen into the circulation but not if the antigen was administered parenterally. There was no demonstrable immunological response by the germ-free mouse to Streptococcus faecalis.

Journal Article↗