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Biomedical subjects

M Poersch

Publications and source records attributed to M Poersch.

10 recordsLinked to original sources

[Return-to-work-therapy in mentally ill employees: experiences with case-management activities by private health insurers].

The development of a "return-to-work-therapy" [RTW-therapy] is described. It was initiated about 3 years ago by case-management teams of private health insurers in Germany to bridge the traditional gap between cure and rehabilitation of mainly depressive employees. The RTW-therapy aims at best-supported recovery of working capacity in patients after partial improvement of their depression. RWT-therapy is a mixture of curative and rehabilitative medicine and incorporates new aspects of case management, i.e. coaching. RWT-therapy tries to overcome (minimise) the depression-induced impairment of working activity mainly by supporting the patients empowerment to start working without a complete recovery of depressive symptoms. The rationale is that a supported recovery to work enhances the positive coping experiences of the patient, which hopefully leads to a further improvement of depressive symptoms. About 24.6 % of the patients managed to start working again after about 16 weeks of RTW-therapy following a continuous sick leave duration of about 63 weeks.

Employment↗

Involvement of cranial muscles and high intermuscular coherence in orthostatic tremor.

Electromyographic recordings were conducted from limb, trunk, and cranial muscles in 6 patients with orthostatic tremor. Spectral analysis revealed a high-frequency tremor not only in the muscles of the limbs and trunk, but also in cranial muscles. The cross spectra were analyzed between various pairs of muscles that displayed a high-frequency tremor pattern. The resulting peak correlations were uniformly very high (near one) suggesting a high level of coherence. The involvement of cranial muscles suggests that supraspinal mechanisms are involved in the generation of orthostatic tremor. The high intermuscular coherence between all muscles indicates the existence of either a unique oscillator that generates tremor in all involved muscles on both sides of the body or a linking mechanism probably at a supraspinal level. The high-frequency tremor was only found when the muscles were contracted isometrically, irrespective of body posture. Thus, tremor generation might be more closely linked to mechanisms responsible for isometric force control than to those involved in stance regulation.

Aged↗

[Acute intermittent porphyria with transient paresis and contracture. Evidence for initial myopathic dysfunction?].

A 70-year old man with acute intermittent porphyria had acute transient bibrachial paresis with moderate contracture of the involved muscles, which showed electrical silence in a conventional electromyographic investigation with surface electrodes placed over the contracted muscle belly (filter: 20 Hz-2 Hz, amplifier 50 microV). Slow finger movements were still possible and showed typical muscle-action potentials. This electroclinical correlation points to myopathic localized dysfunction, perhaps similar to rare case reports with patients having metabolic myopathy of McArdle's type.

Aged↗

[Drug-induced asterixis amplified by relative hypoglycemia].

A 58-year-old man with chronic paranoid-hallucinatoric psychosis had transient episodes with marked paranoid delusions, auditory hallucinations without confusion, shakiness of both upper extremities, tachycardia and sweating. EMG performed with surface electrodes revealed many silent periods in postural active muscles with maximum duration of 120 ms; blood glucose was 65-75 mg/dl. At other times, blood glucose was 135-140 mg/dl, EMG revealed few silent periods in postural active muscles with maximal duration of 50 ms and the patient noted some vibration in his outstretched hands only. Drug-induced asterixis (clozapine, benperidol) amplified by relative hypoglycemia was therefore assumed, and symptoms disappeared after oral antidiabetics were reduced.

Antipsychotic Agents↗

The clinical and prognostic relevance of the postictal slow focus in the electrocorticogram.

Electrocorticograms of 192 complex partial seizures which were recorded via chronically implanted subdural electrodes during presurgical evaluation of 64 patients with medically intractable epilepsy were visually analysed. The objective was to assess the diagnostic and prognostic relevance of postictal slow foci (PISF) in the electrocorticogram which were defined as focal isoelectric activity or as a focal burst-suppression pattern. The following results were obtained: (1) PISF were seen in a total of 114 of 192 seizures (59.4%), (2) 48 of 64 patients (75%) demonstrated at least 1 PISF in 3 seizures, (3) PISF were more frequent in seizures of temporal lobe origin (66%) than in those of extratemporal origin (33.3%), (4) no PISF developed if the electrographic seizure duration was < 32 sec, (5) PISF were (predominantly) localized in the lobe of seizure origin in 85% of the seizures, (6) there was a strong correlation between frequent occurrence of temporal PISF and favourable seizure outcome following temporal lobe surgery. In conclusion, PISF contribute valuable data as to the localization of the epileptogenic zone during presurgical evaluation of epilepsy and indicate favourable seizure outcome following temporal lobe surgery.

Adolescent↗