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Biomedical subjects

M Pluot

Publications and source records attributed to M Pluot.

At least 127 records · Page 7Linked to original sources

[Bronchial granular cell tumor. Apropos of 2 cases].

The authors report two new cases of bronchial granular cell tumour, a site which remains relatively rare. One of these cases was studied from the point of view of histoenzymology and ultrastructure. The appearances seen were identical to those seen in the literature. They lead to the problem of the histogenetics of the lesion, various morphological factors favouring a Schwann cell origin, whilst the presence of "transitional" cells is more in favour of a mesenchymatous origin, or at least the role of mesenchymatous cells in the development of these lesions.

Adult↗

Simultaneous microscopic and biochemical findings in breast carcinoma. Preliminary results.

Intratumoral protein and glucose phosphate isomerase (GPI) content as well as median nuclear DNA amount were determined in breast carcinoma that could be classified by Bloom's grading. These data were analyzed in comparison with TNM classification. Higher protein contents have been displayed in T2 or N+ breast cancers than in T1 or N- tumors. Bloom's grading is strongly correlated to median nuclear DNA content and to some extent with protein and GPI amount. With these results, we have to think about the value of prognostic cytologic criteria. The relationship between intratumoral protein content and prognostic clinical or histological data requires our attention. This would seem to dictate a need for caution in expressing the results of some variables in function of protein content.

Adult↗

Anthrax meningitis. Report of two cases with autopsies.

The authors report two cases of occupation-related anthrax meningitis; one was direct contamination from a diseased animal; the second was due to handling of bone powder imported from India. The pathological pattern of involvement of the meninges and brain is described and discussed.

Adult↗

[Subacute spongiform encephalopathy and Creutzfeldt-Jakob disease. Apropos of 1 case].

The authors describe a case of sub-acute spongiform encephalopathy with an ultrastructural study in a man of 65 with associated dementia, extra-pyramidal syndrome, myoclonia, optical disorders, pyramidal syndrome and speech disorders, rapidly leading to death one and a half months later. Electroencephalograms were at first disorganized with persistent delta and theta activity and only in the last record did short runs of repetitive activity appear. Histologically, there was severe status spongiosus, a moderate degree of neuronal depopulation with a noticeable astrocytary gliosis. Under the electron microscope, the neuropile in the astrocytes was found to be pitted with numerous cavities and so were, to a lesser extent, the axonal projections. The vessels were normal. Nothing was found to indicate viral structures. Attention is drawn to the nosological connection between this type of observation and Creutzfeldt-Jakob disease.

Aged↗