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Biomedical subjects

M Pistolese

Publications and source records attributed to M Pistolese.

At least 37 records · Page 2Linked to original sources

[Atrial demand pacemaker and radio-frequency system in the treatment of brady-tachy syndrome and of recurrent supraventricular tachycardia refractory to drug therapy. Methods and results in eight cases (author's transl)].

The Authors refer on the methods and the results of permanent electrical treatment with atrial demand pacemakers and radio-frequency systems in 6 cases of brady-tachy syndrome and in 2 cases of recurrent supraventricular tachycardia refractory to drug therapy. In the 6 patients with brady-tachy syndrome atrial demand pacemakers with incorporated radiofrequency receiver were employed; in the 2 patients with supraventricular tachycardia a subcutaneous receiver for radiofrequency stimulation was implanted. The catheters employed were: in 3 patients screw-in leads placed in the right atrial appendage and in 5 unipolar sinus coronary leads. The patient-activated transmitter is been realized in two models: the first one can emit short bursts of eight impulses at the rates of 150-220-260 b/m, each one is selectable by the patient; the number and the period of the beats of the second transmitter can be programmed only by one of us; the stimulator is then given to the patient with a personalized fixed program accordingly to the electrophysiological and clinical observations. During a mean follow up of 7.7 months the safety of the leads both for the stability and the electrical behaviour was noticed in all patients but one with a coronary sinus lead in which a stimulation failure was noticed after the eighth month of stimulation because of high threshold requiring the implantation of a ventricular pacemaker. In the brady-tachy syndrome cases the treatment had a considerable antiarrhythmic efficacy, each patient showing a reduction of hyperkinetic episodes and the ability to interrupt them. In the two cases of refractory supraventricular tachycardia a complete control of the episodes by overdrive stimulation was obtained.

Aged↗

[Nocturnal asystolia revealed with Holter monitoring in asymptomatic hypokinetic arrhythmia. Report of two cases (author's transl)].

The Authors report on two cases of hypokinetic arrhythmia with good ventricular rate during the day. In these cases the Holter monitoring showed, during the night, a marked slow down of the cardiac rhythm with short period of cardiac arrest up to 4280 ms. The Authors would like to underline the prognostic and therapeutic importance of the above said remarks, also mentioned by others in the most recent literature, and the necessity to go deeply in to the meaning of these events specially about possibility of sudden death and cerebral hypossia, during the slow down of cardiac rhythm. In both cases a good therapeutic effect, consisting in a complete normalization of the cardiac rate, has been optained with sustained preparation of sympaticomimetic and vagolitic drugs. On the basis of their experience, the Authors think that, in these cases, the pharmacologic therapy, neglected during the last years, could give a good therapeutical result.

Adult↗

[The Italian experience in permanent pacing. A casuistry for more of 10 years: a policentric study (author's transl)].

According to a recent national survey, 387 patients were treated by permanent pacing in 10 Italian centers, between 1961 and 1966. Of these patients 205 have died; 131 (77 males and 54 females) are still alive and no informations could be obtained for the remaining 51 (13%). The overall survival of patients treated during this period of time is therefore not less than 34% which is comparable to that of general population of the same age group. The 131 patients still alive have totaled 1,486 years of pacing and have used up to 784 pacers. Comparing the incidence of the most common causes for replacement during the periods 1961-66 and 1973-77, electrode failures dropped from 21 to 0.9%; circuitry malfunctions occurred in 10.5 and 7.8%; battery depletion rose from 36.8 to 69% of the cases. According to their clinical conditions, the 131 patients on long-term follow-up can be grouped as follows: 62% are in class 1 or 2 of NYHA; 26.7% are in class 3, and 3.8% in class 4. Moreover, 53.4% of patients are living an active life, having some sort of occupation and 29% are holding a driving license.

Aged↗

[The criteria for the choice of a cardiac pacemaker (author's transl)].

The criteria commonly followed for the choice of a cardiac pacemaker to be used in the treatment of AV blocks and sick sinus syndrome are described. In case of AV block, the AA, believe that at first implant a ventricular inhibited pacemaker is to be preferred, while for the replacements the choice will be based on clinical grounds (mainly from the data obtained during the periodic controls, such as persistence of spontaneous activity, failure of sensing, etc.). In case of sick sinus syndrome, ventricular inhibited pacemakers are generally to be preferred firstly to secure stimulation even in case of AV block, secondly for the advantage of a greater stability of the endoventricular catheter. Atrial pacemakers (asynchronous, on demand, or bifocal) will be preferred when the atrial contribution is believed to be important from an haemodynamic point of view. Lastly, in single cases, its is possible to implant radiofrequency devices connected with the electrocatheter for the control of the tachyarrhythmic phases.

Cardiac Pacing, Artificial↗

[Transitory transesophageal atrial electric stimulation. Preliminary report on 19 cases and considerations on the method, indications and results (author's transl)].

Literature provides sufficient evidence that transitory electric stimulation via esophagus (SATE) - after the first positive experimental attempts on dogs - can be applied to man with a simple, rapid and harmless method. The study covers 19 patients subjected to high frequency transesophageal atrial stimulation by way of a bipolar electrode inserted through a nasogastric tube and connected to an external generator capable of producing tension impulses. Said impulses are variable up to 150 volts, lasting 2.5 microsec. with a frequency of up to 450/min. The 19 patients can be divided into 2 groups. The first including 15 patients on which SATE was effected for diagnostic purposes: in coronary deficiency (8 patients), in the disease of sinus node (3 patients), and lastly in the research for the A-V-block latent in 4 patients with acute post-infarctual A-V-block which regressed during the immediate clinical course of the illness. The other group includes 4 patients in which the atrial stimulation indication was the treatment of rapid, paroxysmic atrial rhythms, inaffected by drugs. By using impulses of 25-30 volts, the AA. have obtained a stable stimulation.

Adult↗