Search PubMed⌕ Search

Biomedical subjects

M Pippione

Publications and source records attributed to M Pippione.

At least 37 records · Page 2Linked to original sources
PubMed1995

Agminated Spitz nevi occurring within a congenital speckled lentiginous nevus.

A 40-year-old woman had a speckled lentiginous nevus on her thigh since birth. During her first pregnancy, additional papules and nodules appeared within the preexisting hyperpigmented area, histologic examination of which showed features of both junctional and compound Spitz's nevi accompanied by simple lentigolike changes. In this particular case, speckled lentiginous nevus may have constituted a particular environment for the production of multiple Spitz nevi.

Adult↗
PubMed1994

Chronic venous stasis: not a predisposing factor for basal cell carcinoma on the leg. A histopathological study.

A histopathological study of 125 cases of basal cell carcinoma (BCC; out of 5,475 over a period of 5 years) occurring on the leg was performed. Nodular and superficial BCC were the most common patterns. No sclerosing type was observed, although prominent fibrosis was present in some cases of BCC associated with severe stasis changes. Stasis changes were found only in 25% of the cases suggesting that they do not represent a predisposing factor for the development of BCC on the leg.

Aged↗
PubMed1994

Vulvar intraepithelial neoplasia of low grade: a challenging diagnosis.

The authors reviewed 21 cases of "mild vulvar atypia" diagnosed from 1981 to 1990. The first 16 cases were diagnosed as hyperplastic dystrophy with mild atypia according to the 1976 ISSVD Classification of Vulvar Disease, while the last five cases were diagnosed as vulvar intraepithelial neoplasia grade I (VIN I). The review of the specimens was made by the same pathologist who gave the initial diagnosis and by a dermatopathologist unaware of the initial diagnosis. Both reviewers used the 1986 and 1989 ISSVD terminologies. The presence of "mild atypia" was confirmed in only four of the 21 specimens, that is in 19% of the cases, and two of them were found in the context of patients suffering from a lichen planus. These findings show that the diagnosis of mild atypia in vulvar tissues is a challenge and that mild vulvar atypia cannot be automatically considered a VIN I.

Adult↗
PubMed1993

Microvenular hemangioma.

We report five cases of microvenular hemangioma, a recently described benign vascular disorder. Clinically, they were acquired, slowly enlarging angiomatous lesions without distinctive features. Histologically, these tumors were characterized by a proliferation of small-sized, irregularly branched, blood vessels throughout the dermis embedded in a desmoplastic stroma. In many areas, the endothelial cells were surrounded by pericytes. The architectural pattern of microvenular hemangioma make its differentiation possible from other cutaneous benign vascular lesions, namely, capillary hemangioma, lobular capillary hemangioma, angioblastoma, and hemangiomas in polyneuropathy, organomegaly, endocrinology, M protein, skin changes (POEMS) syndrome. A close relationship among these vascular proliferations is suggested.

Adult↗
PubMed1993

Seborrheic keratosis-like lesions in epidermodysplasia verruciformis.

A light microscopic study of 6 verrucous lesions with clinical features of seborrheic keratoses (SK) occurring on sun-exposed skin of 4 patients with epidermodysplasia verruciformis (EV) was performed. We observed the typical histological findings of SK in all cases. In addition, koilocytotic effects suggestive of EV were observed in the upper prickle layer and stratum granulosum. In 2 lesions, we also noted bowenoid changes suggesting possible early malignant transformation. Immunohistochemical study confirmed the presence of HPV in these lesions.

Adult↗
PubMed1993

Mycosis fungoides and eruptive epidermoid cysts: a unique response of follicular and eccrine structures.

A case of a patient who developed simultaneously mycosis fungoides (MF) and multiple, tiny eruptive cutaneous cysts on the face, neck and upper part of the trunk is reported. Histologically and immunohistochemically MF infiltrate was recognized not only in the upper part of the dermis and in the epidermis but also around and within the walls of cystic lesions. Furthermore, the eccrine structures were also involved by MF infiltrate. We emphasize that MF infiltrate can affect the follicular and eccrine structures inducing the formation of keratinous cysts. The clinical appearance of the facial lesions may be confused with Favre-Racouchot disease.

Aged↗
PubMed1993

Cutaneous lymphadenoma. A basal cell carcinoma with unusual inflammatory reaction pattern?

Two additional cases of cutaneous lymphadenoma (CL) are reported. The lesions presented as single nodules of many years' duration on the face. Histologically, the neoplasms consisted of irregularly shaped lobules immersed in a dense fibroblastic stroma involving the whole dermis and extending into the subcutaneous fat. Duct-like structures suggesting an eccrine differentiation were recognized. The lobules were composed of a rim of basaloid cells surrounding large epithelioid cells and lymphocytes. In some areas the basaloid lobules were only partly replaced by the inflammatory cells. Immunohistochemically, the intralobular inflammatory component was composed of a mixed B- and T-cell population and S-100-positive dendritic cells. The observation of these cases suggests that CL is not a distinct entity but may represent a basal cell carcinoma, possibly with pilar or eccrine differentiation, in which an immune host reaction pattern is exceedingly unusual.

B-Lymphocytes↗
PubMed1992

HPV-related follicular cysts.

Five examples of follicular cysts with papillary projections protruding into the lumen are given. In all cases, the lining was epidermoid. The cystic cavity contained compact, eosinophilic keratinous material. Groups of vacuolated keratinocytes with overlying tiers of parakeratotic cells were seen on the top of the crests. In the intervening valleys, there were irregular clumps of keratohyaline granules. These changes are diagnostic cytopathogenic effects of viral papillomas. However, papillomavirus common antigens were not identified by immunohistochemistry.

Adult↗
PubMed1992

Pigmented trichoblastoma.

We report a case of trichogenic tumor with epithelial and mesenchymal components recapitulating the formation of hair germs. The epithelial lobules were highly pigmented and affected the full thickness of the dermis, extending into the subcutaneous fat. In addition, amyloid deposits were found within the epithelial lobules and in the stroma. The overall architecture was reminiscent of hair bulbs. Problems of differential diagnosis with other trichogenic tumors and pigmented tumors are discussed.

Adipose Tissue↗
PubMed1992

Eccrine angiomatous hamartoma: a multiple variant.

A case of multiple eccrine angiomatous hamartoma present in a boy since birth is reported. Clinically, this condition must be differentiated from other neonatal angiomatoses. Sometimes the clinical findings are nonspecific, whereas histologic examination may exclude angiomatoses with visceral involvement. In our case the hamartomatous nature of this tumor is documented also by the presence of pilar structures intimately related to the eccrine-angiomatous complex in one of two lesions histologically examined. Therefore, the histologic classification of eccrine angiomatous hamartoma into subgroups seems to be excessive.

Child, Preschool↗
PubMed1989

Parakeratotic horns in a patient with Crohn's disease.

Horny finger-like lesions can be observed in many dermatoses. In some cases the clinical features suggest the diagnosis, but only the histological examination will confirm it. Our purpose here is to describe a case of multiple parakeratotic horns occurring in a patient with Crohn's disease.

Adult↗
PubMed1989

[Eccrine angiomatous nevus].

A case of eccrine angiomatous nevus of the leg in a 21 year-old woman is reported. The lesion present since birth was painful on pressure and exhibited hyperhidrosis. Histological examination of the lesion showed an increased number of eccrine structures without structural abnormalities with an angiomatous vascular component. In addition, there were some neural sheets. Problems of differential diagnosis and histogenesis of the eccrine angiomatous hamartoma are discussed.

Adult↗
PubMed1988

Basal cell carcinoma with matrical differentiation. Matrical carcinoma.

Three unusual cases of basal cell carcinoma showing matrical differentiation as evidenced by the focal presence of "shadow cells" within basaloid islands are described. The term basal cell tumor with matrical differentiation seems to be appropriate for this type of tumor. Its differentiation from other tumors, particularly malignant pilomatricoma, is also discussed.

Aged↗
PubMed1988

Balloon cell melanoma: a report of two cases.

Two cases of balloon cell malignant melanoma of the skin are reported. The first lesion was pigmented, the second was amelanotic. Histologically, the tumor mass was dermal and intraepidermal and almost exclusively composed of balloon cells. Many of the clear cells demonstrated postivity with the S-100 protein immunostaining. The problems of clear-cell tumor differential diagnosis are discussed.

Aged↗
PubMed1988

[Nevus sebaceous].

Explore the source record for details and available documents.

Dermatitis, Seborrheic↗
PubMed1987

Sea-blue histiocyte syndrome with cutaneous involvement. Case report with ultrastructural findings.

A patient with infiltration of the skin resulting in eyelid swelling and facial nodules was recognized as a case of sea-blue histiocyte syndrome with cutaneous involvement. Typical sea-blue histiocytes were found in the skin and confirmation was provided by electron microscopy. Hepatosplenomegaly, lung infiltrates and bone marrow involvement were the other symptoms. The relationship between sea-blue histiocyte syndrome and adult Niemann-Pick disease is also discussed.

Adult↗