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Biomedical subjects

M Piccioni

Publications and source records attributed to M Piccioni.

6 recordsLinked to original sources
PubMed2004

Laparoscopic cryomyolysis: an alternative to myomectomy in women with symptomatic fibroids.

BACKGROUND: The purpose of this study was to determine whether cryomyolysis may present an alternative valid surgical procedure to hysterectomy or myomectomy for selected women with symptomatic fibroids who wish to preserve their uterus but do not desire future pregnancies. METHODS: Sixty-three women with symptomatic fibroids who refused either myomectomy or hysterectomy, requesting a conservative surgery for myomata, underwent laparoscopic cryomyolysis using a 3- to 5-mm or 8-mm cryoprobe (CRYOcare system). RESULTS: Our study showed a mean (+/-standard deviation) decrease of myoma volume of 60.3% (+/-20.7) and complete symptom relief in 83.6% (p < 0.001) of patients after a 12-month follow-up from cryomyolysis. No significant intra- or postoperative complications were noted. CONCLUSION: Cryomyolysis is an effective laparoscopic procedure for obtaining myoma shrinkage and symptom relief in women with symptomatic fibroids who desire to preserve their uterus.

Adult↗
PubMed2001

Slow dynamics and aging in a constrained diffusion model.

We carry out a complete analysis of the schematic diffusive model recently introduced for the description of supercooled liquids and glassy systems above the glass temperature. The model is described by a trivial equilibrium measure and the presence of kinetics constraints is mimicked through a rapidly decreasing mobility at high particle density. The governing equation describing a sudden quench process is investigated analytically in a mean field approach and by means of numerical simulations. For deep quenches a long lasting off-equilibrium dynamics is observed in dense systems before equilibration is achieved, where time translational invariance lacks and the system ages. The kinetics is slow in this time domain since the average particle diffusivity D decreases in time, as opposed to the standard diffusion case of a constant D, that is recovered only in equilibrium. The autocorrelation function decays slower than an exponential, falling in mean field as an enhanced power law. The linear response function is computed and the modalities of the break-down of the fluctuation dissipation theorem are analytically investigated, showing that an effective temperature can be defined which slowly approaches the bath temperature from above.

Journal Article↗