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Biomedical subjects

M Peneva

Publications and source records attributed to M Peneva.

12 recordsLinked to original sources

[Evaluation of immunostimulating agents used in pulmonologic practice].

Several immunostimulating drugs--levamisole (decaris), Gamma-A, dipyridamole (Antistenocardin), Respivax--were included in the treatment of 161 patients with frequently recurring chronic nonspecific lung diseases and data for suppression of various components of the immune system. Levamisole and Respivax show marked antirelapse efficacy in chronic lung diseases. Gamma-A has a certain immunosubstituent action, dipyridamole exerts a moderate antirelapse action.

Adjuvants, Immunologic↗

[Respiratory function study of workers engaged in vinyl chloride and polyvinyl chloride manufacture].

A hygienic evaluation is made on the work conditions in the production of vinyl chloride and polyvinyl chloride. Studies were carried out on 516 workers after the following indices: vital capacity /VC/, forced expiratory volume per sec. /FEV1/, peak expiratory capacity /PEC/, maximum expiratory capacity 75 /MEC75/, maximum expiratory capacity 50 /MEC50/ and maximum expiratory capacity 25 /MEC25/. It was established that 33.13% of the workers were with ventilation disturbances. The most frequently met was the obstructive syndrome of ventilation insufficiency. The infringements were most often in workers with length of service up to 1 year.

Adult↗

[Pleural effusions of neoplastic etiology].

A prospective analysis was made of 50 patients with neoplastic pleural exudation for the period 1977-1979. Twenty five of the patients (50%) are with advanced age (60-75). Bronchogenic carcinoma is the most often primary localization of the neoplastic exudates --26 patients (52%), followed by mammary carcinoma--10 cases (20%). In 76 per cent of the patients the pleural exudation is the first clinical manifestation of the neoplastic disease. In the rest of the cases, the metastatic exudation was manifested by the third year after the diagnosis of primary tumor. Dyspnea is outlined as a leading clinical symptom. The data from the biochemical and cytological studies of the pleural punctate were analyzed. The cytological finding is with the highest diagnostic value for the neoplastic pleural exudates.

Adult↗

[Analgetic and anti-inflammatory action of glaucine].

The authors examined the analgetic and antiinflammatory action of glaucine. They used the following methods for evaluation the analgetic action: chemical irritation, heating plate, heat-ray irritation, mechanical irritation of the normal and inflammatory tissues, electrical irritation and analgetic test. The following methods were used for evaluation of antiinflammatory action: effect on the edema of the rat paw and granulation phases of the inflammation in rats. Codeine and acetysal were used as control drugs. The results from the experiments showed that glaucine successfully inhibited the granulation phase of inflammation and did not affect edema of the rat paw, induce by yeast beer. The analgetic action of glaucine was weak and without practical significance.

Animals↗

[Influence of salivary gland hormone on the number of leukocytes and level of calcium in the blood of experimental rabbits].

The authors examined the influence of single venous doses of hormone from the saliva glands on the calcium level and leucocytes in the blood of nonnarcotized experimental rabbits. They investigated the effect in the following doses: 20, 10.5 and 1 mg/kg of body weight. The indicated two indices were examined 2, 4, 6 and 10 hours after the injection of the preparation. The venous administration of all exa mined doses of the hormone from the saliva glands caused statistically significant lowering of leucocytes on the second hour and respective increase on the sixth and tenth hour since the onset of the experiment. The hormone of the saliva glands lowered the amount of calcium ions in blood, but the difference was not always statistically significant in various doses and time intervals.

Animals↗

[Not Available].

In the past 50 years, Soviet forensic psychiatry has directed its main endeavours towards solution of the problems of organization of forensic psychiatric expert examination, finding the most appropriate forms of handling law offenders--mental patients--as well as towards elucidation of the phenomenology of the morbid process under conditions of preliminary inquest, with prison, and finding with greatest precision the criteria for irresponsibility and incapacity in various diseases.

Communism↗

[Hypomineralization of milk teeth of prematurely born children--effect of some factors for its origination].

A comparative study was carried out between two groups of children--115 prematurely born and 4830 full-term babies in order to establish the effect of pregnancy duration of the origination of hypomineralization of the milk teeth. The effect of the following factors was also studied and compared: complications of pregnancy, feeding of the newborn and diseases during early childhood of full-term and prematurely born children. The authors established that the prematurely born children were a risk group for the origination of milk teeth hypomineralization. The complications of pregnancy, mixed or bottle feeding as well as the frequent illnesses are additional aggravating factors in the origination of milk teeth hypomineralization. The authors recommend timely follow-up care and prophylaxis of all prematurely born children.

Bottle Feeding↗

[Dental caries with chronic renal insufficiency].

Chronic renal insufficiency (CRI) is an irreversible lesion of the renal function with advancing of renal rickets, dyselectrolythemia, azotemic osteodystrophia in the bones. On the background of all those severe changes in organism, low indices of dental caries epidemicty are cited in literature. A total of 30 children with CRI were examined: Group 1--21 children with disease onset immediately after birth and duration from 5 to 15 years and group 2--9 children with disease onset after the age of 7 and duration from 2 to 5 years. The intensity of caries and epidemicty were compared according to milk and permanent teeth with a group of healthy children (900). A four-time higher urea level was established in group 1, reduced calcium and increased phosphorus. The children with CRI were less affected by dental caries as compared with the healthy ones, being better manifested in case of an earlier onset and longer duration of the disease. The problem of the future is the explanation of the phenomenon observed and the results--used in prophylasxis.

Adolescent↗