Biomedical subjects
M Peck
Publications and source records attributed to M Peck.
Patient-triggered synchronized assisted ventilation of newborns. Report of a preliminary study and three years' experience.
The safety, efficacy, and outcome of long-term patient-triggered synchronized assisted ventilation in infants (SAVI) was studied in very low birthweight infants (450 to 1250 g) with uncomplicated respiratory failure. Synchronization was accomplished by modified thoracic impedance technology using standard neonatal cardiorespiratory monitors with the output of the ventilation synchronizer triggering the exhalation solenoid of a standard neonatal respirator. In this nonrandomized study, the technique was found to be safe and reliable without any episodes of technical failure or adverse effects. The results indicated that in comparison with infants receiving conventional ventilation, infants receiving SAVI required (1) shorter duration of ventilation, (2) decreased duration of oxygen therapy, and (3) decreased progression of intraventricular hemorrhage to greater than or equal to grade III. Decreased duration of ventilation was statistically significant in infants weighing less than 850 g (P less than .02). These beneficial trends were ratified during a 3-year period in a total of 110 cases.
Preventive dentistry in private practice: a survey of Massachusetts offices.
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Multiply-antibiotic-resistant Haemophilus influenzae type b meningitis in Western Australia.
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Isolated hypoaldosteronism and abnormalities in renin, kallikrein, and prostaglandin.
To further define the pathophysiology of the syndrome of acquired isolated hypoaldosteronism, we determined plasma concentrations of active and inactive renin and urinary kallikrein and prostaglandin E2 excretion rates in 11 patients with the syndrome, 12 patients with similar serum creatinine levels, but without hyperkalemia, and in 12 normotensive patients with normal renal function and low plasma renin activities (PRA). Ten of 11 patients with the syndrome had low baseline PRA, and, unlike the control groups, six of 11 failed to double their PRA after furosemide stimulation. There were also consistent abnormalities in the percentage of inactive renin, no patient having a value less than and no control subjects having a value greater than 65%. Seven of 11 patients had prostaglandin E2 excretion rates lower than either control groups. Urinary kallikrein excretion rates in the patients with isolated hypoaldosteronism were significantly lower than in the control groups, but increased in response to therapy with fludrocortisone.
Patient survival with liver metastases from colorectal cancer--a district hospital experience.
In a retrospective review of 301 newly diagnosed tumours of the colon and rectum, 61 patients (20%) presented with liver metastases. The mean survival for this group was 7.4 months. Five patients with solitary metastases were found who may have been helped by further surgery. There was a 20% operative mortality. No significant association between the grade, differentiation, lymph node status or venous invasion of the primary lesion was demonstrated. Operative palliative resection of the primary lesion did not improve survival. These results confirm the poor prognosis for patients with liver metastases, justifying all efforts into the earlier detection and prevention of colorectal carcinoma.
Neonatal narcotic withdrawal diagnosis and treatment.
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