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Biomedical subjects

M Pavlova

Publications and source records attributed to M Pavlova.

26 records · Page 2Linked to original sources
PubMed1993

Biocompatible and biodegradable polyurethane polymers.

This study deals with the opportunities for the synthesis of biocompatible and biodegradable polyurethane adhesives which are suitable for application as wound dressings. Three different synthetic possibilities have been investigated. The relationships between some reaction factors and the final properties of the obtained products are pointed out. The toxicity of the investigated urethane acrylates, polyurethanes and combined polyurethane adhesives is also studied.

Acrylates↗
PubMed1990

[The nephrotic syndrome as a consequence of Feloran treatment in a female patient with rheumatoid arthritis].

A case is presented of a 65 years old woman with a rheumatoid arthritis III stage who had developed a nephrotic syndrome due to the treatment with Feloran. The biopsy examination showed the pathomorphologic pattern of glomerulonephritis with minimum changes. The discontinuance of the Feloran treatment led to a full disappearance of the nephrotic syndrome. It is recommended that Feloran treatment should not be applied to patients with previous renal lesions.

Aged↗
PubMed1989

Expression of synthetic calcitonin genes in plasmid vectors containing tandemly repeated non-overlapping ribosome binding sites.

1. Expression plasmids containing non-overlapping tandemly repeated ribosome binding sites (RBS) were constructed in order to stabilize mRNA and enhance translation. 2. Two synthetic genes (human calcitonin tetramer gene and a fusion gene human gamma-interferon-human calcitonin) were cloned in these vectors and the effect of multiplicity of Shine-Dalgarno (S/D) sequence on heterologous gene expression was studied. 3. It was found that duplication and triplication of RBS had no effect on the stability of mRNA but led to a strong decrease in the level of recombinant protein and mRNA in the cell. 4. Plasmids bearing four times repeated S/D sequences gave longer-lived mRNAs and maintained a level of protein and mRNA very close to the values obtained with a single S/D containing plasmids.

Base Sequence↗