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Biomedical subjects

M Pap

Publications and source records attributed to M Pap.

7 recordsLinked to original sources

The influence of religious affiliation on surname repetition in marriages in Tiszaszalka, Hungary.

The repeated-pairs of surnames in marriages (RP) approach is applied to the population of Tiszaszalka in north-eastern Hungary. The results indicate that: (1) lineage-like behaviour in mate choice results in population subdivision in both the Catholics and the Protestants of the village; (2) unlike in some other Tiszahat villages, the isonymous and the repeating unions in Tiszaszalka occur in different lineages so, in neither of these subpopulations are isonymous and repeating unions monopolised by a few lineages; (3) religious affilitation influences the mating structure of the population as measured by RP summary scores.

Choice Behavior

Surname repetition and isonymy in northeastern Hungarian marriages.

The repeated-pair (RP) approach to surnames in married couples is a measure of population subdivision resulting from the influence of lineagelike behavior in mate choice. An excess of RP over random RP implies limitations in mate choice and a reduction of genetic variability. Here we apply the RP method to data from the rural populations of Csaroda, Tiszaadony, and Tiszavid in northeastern Hungary. The results indicate small differences between RP and random RP for Tiszavid and somewhat larger differences for Tiszaadony and Csaroda. The excess of RP over random RP in Tiszavid, however, derives primarily from marriages simultaneously isonymous and repeating in only one lineage. The discrepancy between RP and random RP implies a small reduction in genetic variability.

Consanguinity

Severe growth failure associated with atrophic intestinal mucosa and ring chromosome 15.

Ring chromosome 15 was detected in a boy with severe growth failure and no dysmorphic features who had previously been found to have an atrophic intestinal mucosa, a finding not observed in about 300 patients with ring autosome reported so far. Of the 137 metaphases examined, 8.1% had secondary aneuploidy produced by the structural and behavioural instability of the ring. Ring derivatives could also be seen in lymphocytes after only one cycle in the culture, indicating that such cells are also generated in vivo. We observed an increased cell death rate in fibroblast culture by Trypan Blue exclusion. These results suggest that there is a continuous in vivo generation of cells with increased mortality resulting in both growth failure and atrophic intestinal mucosa in the patient. The atrophic intestinal mucosa might be a manifestation of ring instability.

Atrophy

Prevalence of minor congenital anomalies in diabetic children.

The prevalence of 52 minor congenital anomalies (MCAs) was determined in 111 children with insulin dependent diabetes mellitus (IDDM), and in 111 healthy matched control subjects. The average MCA per person was 1.60 in diabetic children and 0.86 in the controls (p less than 0.001). The difference was exclusively due to the significantly higher proportion of subjects with 3 or more MCAs in the diabetic group (27.0 versus 9.9%; p less than 0.001). No specific MCA characteristic of IDDM was found.

Adolescent